64699-01-0

Basic information

• Product Name: t-butyloxycarbonyl-glutamyl-phenylalanyl-phenylalanyl-glycyl-leucyl-methionine amide
• Synonyms: t-butyloxycarbonyl-glutamyl-phenylalanyl-phenylalanyl-glycyl-leucyl-methionine amide
• CAS NO: 64699-01-0
• Molecular Weight: 841.042
• Mol File: 64699-01-0.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: t-butyloxycarbonyl-glutamyl-phenylalanyl-phenylalanyl-glycyl-leucyl-methionine amide(CAS DataBase Reference)
• NIST Chemistry Reference: t-butyloxycarbonyl-glutamyl-phenylalanyl-phenylalanyl-glycyl-leucyl-methionine amide(64699-01-0)
• EPA Substance Registry System: t-butyloxycarbonyl-glutamyl-phenylalanyl-phenylalanyl-glycyl-leucyl-methionine amide(64699-01-0)

Safety Data

• Hazardous Substances Data: 64699-01-0(Hazardous Substances Data)

Upstream product

• 73994-96-4 Boc-Gly-Leu-Met-OMe 
• 72217-96-0 H-Leu-Met-OCH₃ 
• 2280-69-5 Boc-Leu-Met-OMe 
• 10332-17-9 Met-OMe 
• 13726-85-7 Boc-Gln-OH 
• 73148-99-9 N-t-Boc-Phe-Phe-Gly-Leu-Met-NH₂ 
• 83181-66-2 Boc-Phe-Phe-Gly-Leu-Met-OCH₃ 
• 77511-07-0 t-butyloxycarbonyl-glutamyl-phenylalanyl-phenylalanine 
• 101301-81-9 Boc-Gln-Phe-Phe-Gly-OMe 
• 2280-68-4 N-tert-butoxycarbonyl-L-leucyl-L-methioninamide 
• 13139-15-6 N-tert-butoxycarbonyl-L-leucine 
• 77511-06-9 t-butyloxycarbonyl-glutamyl-phenylalanyl-phenylalanine methyl ester 
• 4892-10-8 N-(benzyloxycarbonyl)-L-phenylalanyl-L-phenylalanine methyl ester 
• 2578-84-9 N-benzyloxycarbonyl-L-phenylalanine p-nitrophenyl ester 

Downstream Products

• 84640-76-6 (S)-2-((S)-2,5-Diamino-pentanoylamino)-pentanedioic acid 5-amide 1-({(S)-1-[(S)-1-({[(S)-1-((S)-1-carbamoyl-3-methylsulfanyl-propylcarbamoyl)-3-methyl-butylcarbamoyl]-methyl}-carbamoyl)-2-phenyl-ethylcarbamoyl]-2-phenyl-ethyl}-amide) 
• 56104-20-2 (S)-2-Amino-pentanedioic acid 5-amide 1-({(S)-1-[(S)-1-({[(S)-1-((S)-1-carbamoyl-3-methylsulfanyl-propylcarbamoyl)-3-methyl-butylcarbamoyl]-methyl}-carbamoyl)-2-phenyl-ethylcarbamoyl]-2-phenyl-ethyl}-amide); hydrochloride 
• 51165-07-2 glutamyl-phenylalanyl-phenylalanyl-glycyl-leucyl-methionine amide 

Relevant articles and documents

Design, synthesis, and evaluation of substance P analogue with potential anti-pseudoallergic activity

Mast cells (MCs) are innate immune cells that can cause allergic reactions. Pseudo-allergic reactions are a type of reaction that have the clinical symptoms of an allergy without involving the IgE pathway of immune MCs. Some studies have found that the MR

α-Chymotrypsine catalyzed peptide syntheses using the 4-sulfobenzyl rests as dissolving carboxyl protecting group

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SYNTHESIS OF HEXAPEPTIDES FRAGMENT OF SUBSTANCE P AND ITS PYROGLUTAMYL-ANALOG

Syntheses of Substance P, C-terminal hexapeptide fragment (Gln-Phe-Phe-Gly-Leu-Met-NH2), and its pyroglutamyl-analog which is formed as a by-product on decoupling step in synthesis of C-terminal hexapeptide fragment of substance P are described.