6476-52-4Relevant articles and documents
A New Approach for the Synthesis of Perfluoroalkanesulfenic Acids
Xu, Jia-Hong,Jiang, Min,Song, Li-Ping,Liu, Jin-Tao
, p. 1919 - 1923 (2021)
A new and more practical method for the preparation of solution-stable perfluoroalkanesulfenic acids was successfully developed. Starting from perfluoroalkyl iodides, perfluoroalkyl sulfoxides were synthesized by their substitution reaction with alkyl mercaptans and the following oxidation of resulting perfluoroalkyl sulfides with m-CPBA. Subsequent β-H elimination of perfluoroalkyl sulfoxides under heating conditions gave the corresponding perfluoroalkanesulfenic acids in good yields.
Ionic Liquids for Fast and Solvent-Free Nucleophilic Trifluoromethylthiolation of Alkyl Halides and Alcohols
Anselmi, Elsa,Simon, Cédric,Marrot, Jér?me,Bernardelli, Patrick,Schio, Laurent,Pégot, Bruce,Magnier, Emmanuel
supporting information, p. 6319 - 6326 (2017/11/21)
The trifluoromethylthio group is of rising interest in medicinal, agrochemical, and materials chemistry. Although several strategies for the introduction of this functional group have been described, new synthetic methods are needed. A novel ionic liquid, 1-n-butyl-3-methylimidazolium trifluoromethylthiolate, has been developed and is herein reported as an efficient and recyclable in situ generated trifluoromethylthiolating reagent for alkyl halides, sulfonates, and even unactivated alcohols under solvent-free conditions.
Oxidative decarboxylative radical trifluoromethylthiolation of alkyl carboxylic acids with silver(i) trifluoromethanethiolate and selectfluor
He, Bin,Xiao, Zhiwei,Wu, Hao,Guo, Yong,Chen, Qing-Yun,Liu, Chao
, p. 880 - 883 (2017/01/13)
A straightforward silver-mediated oxidative decarboxylative radical trifluoromethylthiolation reaction of aliphatic carboxylic acid is described. This reaction operates under mild conditions and allows the synthesis of various valuable alkyltrifluoromethylthioethers from abundant alkyl carboxylic acids and convenient nucleophilic AgSCF3 reagent. It provides a practical and efficient approach for the preparation of alkyltrifluoromethylthioethers.