648939-10-0

Basic information

• Product Name: 5-chloro-2-(2,2,2-trifluoroacetyl)aminobenzoic acid
• Synonyms: 5-chloro-2-(2,2,2-trifluoroacetyl)aminobenzoic acid
• CAS NO: 648939-10-0
• Molecular Weight: 267.592
• Mol File: 648939-10-0.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 5-chloro-2-(2,2,2-trifluoroacetyl)aminobenzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 5-chloro-2-(2,2,2-trifluoroacetyl)aminobenzoic acid(648939-10-0)
• EPA Substance Registry System: 5-chloro-2-(2,2,2-trifluoroacetyl)aminobenzoic acid(648939-10-0)

Safety Data

• Hazardous Substances Data: 648939-10-0(Hazardous Substances Data)

Upstream product

• 635-21-2 5-chloroanthranilic acid 
• 407-25-0 trifluoroacetic anhydride 

Downstream Products

• 573692-30-5 2-amino-5-chloro-N,N-diethyl-3-nitrobenzamide 
• 573692-43-0 2,3-diamino-5-chloro-N,N-diethyl-benzamide 
• 573692-29-2 2-amino-5-chloro-N,N-dimethyl-3-nitrobenzamide 
• 40545-37-7 2-amino-5-chloro-3-nitrobenzamide 
• 573692-42-9 2,3-diamino-5-chloro-N,N-dimethyl-benzamide 
• 573692-41-8 2,3-diamino-5-chlorobenzamide 
• 84228-49-9 methyl 2-amino-5-chloro-3-nitrobenzoate 
• 314248-61-8 methyl 2,3-diamino-5-chlorobenzoate 
• 37901-82-9 2,3-diamino-5-chlorobenzoic acid 
• 6324-51-2 2-amino-5-chloro-3-nitrobenzoic acid 
• 573692-70-3 5-chloro-3-nitro-2-(2,2,2-trifluoroacetyl)aminobenzoic acid 

Relevant articles and documents

NOVEL MITOCHONDRIAL UNCOUPLERS FOR TREATMENT OF METABOLIC DISEASES AND CANCER

The present disclosure relates to benzamide compounds, prodrugs of the compounds, pharmaceutical compositions containing the compounds and/or the prodrugs and methods of using the compounds, prodrugs and pharmaceutical compositions in the treatment of diseases related to lipid metabolism including diabetes, Non-Alcholic Fatty Liver Disease (NAFLD), Non-Alcholic Steathohepatitis (NASH), diseases caused by abnormal cell proliferation including cancer, psoriasis, and infectious diseases.

Synthesis and SAR of novel di- and trisubstituted 1,4-dihydroquinoxaline-2,3-diones related to licostinel (Acea 1021) as NMDA/glycine site antagonists

A series of novel di- and trisubstituted 1,4-dihydroquinoxaline-2,3-diones (QXs) related to licostinel (Acea 1021) was synthesized and evaluated as antagonists for the glycine site of the N-methyl-D-asparate (NMDA) receptor. The in vitro potency of these