65094-25-9Relevant articles and documents
A new route to α-fluorovinylphosphonates utilizing Peterson olefination methodology
Waschbuesch, Rachel,Carran, John,Savignac, Philippe
, p. 14199 - 14216 (1996)
Several α-fluorovinylphosphonates (6) have been synthesised from the Peterson olefination reaction applied to both aldehydes and ketones in conjunction with α-lithiated-α-fluoro-α-trimethylsilylmethylphosphonates (2). The reaction with aldehydes gives mainly the E-isomer whereas reaction with ketones gives mainly the Z-isomer. We propose a closed transition state to explain the results of our study.
An efficient synthesis of tetraethyl fluoromethylenediphosphonate and derivatives from diethyl dibromofluoromethylphosphonate
Iorga, Bogdan,Eymery, Frederic,Savignac, Philippe
, p. 4477 - 4480 (1998)
Treatment of diethyl 1,1-dibromo-1-fluoromethylphosphonate with n-BuLi (1:1) at low temperature affords by self-trapping in quantitative yield the lithiated derivative of tetraethyl fluoromethylenediphosphonate which is reacted with alkylating and halogenating agents or converted with high selectivity into (E) diethyl fluorovinylphosphonates by reaction with carbonyl compounds.
Preparation of triethyl 2-fluoro-2-phosphonoacetate
Patois,Savignac
, p. 1317 - 1322 (2007/10/02)
Triethyl 2-fluoro-2-phosphonoacetate was prepared in one step from dibromofluoromethyl phosphonate and ethyl chloroformate.
