65160-71-6

Basic information

• Product Name: D-Tyrosine, N-acetyl-, methyl ester
• CAS NO: 65160-71-6
• Molecular Formula: C12H15NO4
• Molecular Weight: 237.255
• Mol File: 65160-71-6.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: D-Tyrosine, N-acetyl-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: D-Tyrosine, N-acetyl-, methyl ester(65160-71-6)
• EPA Substance Registry System: D-Tyrosine, N-acetyl-, methyl ester(65160-71-6)

Safety Data

• Hazardous Substances Data: 65160-71-6(Hazardous Substances Data)

Upstream product

• 125718-58-3 methyl (Z)-2-acetamido-3-(4-hydroxyphenyl)acrylate 
• 128459-09-6 N-acetyl-N-methoxyacetamide 
• 1080-06-4 L-Tyr-OCH₃ 
• 108-24-7 acetic anhydride 
• 3728-20-9 D-tyrosine methylester hydrochloride 
• 127-09-3 sodium acetate 
• 23525-90-8 2-acetylamino-3-(4-hydroxyphenyl)propionic acid methyl ester 
• 3410-66-0 D-tyrosine methyl ester 

Downstream Products

• 900521-27-9 methyl (2R)-2-acetamido-3-(4-allyloxyphenyl)propanoate 
• 126204-63-5 (R)-2-Acetylamino-3-{4-[3-((R)-amino-methoxycarbonyl-methyl)-phenoxy]-phenyl}-propionic acid methyl ester 

Relevant articles and documents

A highly effective phosphinite ligand derived from D-mannitol for Rh- catalyzed asymmetric hydrogenation

A novel chiral phosphinite 1,2,5,6-di-isopropylidene-3, 4- bis(diphenylphosphino)-D-mannitol was prepared and its rhodium complex was found to be an effective catalyst for the asymmetric hydrogenation of amidoacrylic acid and its derivatives with product ee's ranging from 90% to 97%.

PEPTIDIC COMPOUNDS

The present invention provides a compound of formula (I), (II), (III) and (IV) as defined herein and pharmaceutically acceptable derivatives thereof. The present invention further provides use of the compounds of the present invention in the treatment of bacterial infection and in the treatment of HIV infection. Also provided are pharmaceutical compositions comprising the compounds of the present invention.

Studies on the Synthesis of Aryl Ethers Using Arene-Manganese Chemistry

Selective arylation of polyfunctional phenols, using chlorobenzene- and p-chlorotoluene-manganese tricarbonyl cations, is described.The intermediate arene-manganese complexes are found to undergo stereo- and regioselective reactions with Schoellkopf's chiral glycine enolate equivalent to give dienyl-Mn(CO)3 complexes.Treatment of these complexes with N-bromosuccinimide at room temperature, followed by hydrolysis of the dihydropyrazine, gives diaryl ethers in which one of the aromatic rings is an arylglycine methyl ester.