651780-33-5

Basic information

• Product Name: Ethanone, 1-(6-broMo-1H-indazol-1-yl)-
• Synonyms: Ethanone, 1-(6-broMo-1H-indazol-1-yl)-;1-(6-bromo-1H-indazol-1-yl)ethanone;1-(6-Bromo-indazol-1-yl)-ethanone
• CAS NO: 651780-33-5
• Molecular Formula: C9H7BrN2O
• Molecular Weight: 239.06868
• Mol File: 651780-33-5.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Ethanone, 1-(6-broMo-1H-indazol-1-yl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Ethanone, 1-(6-broMo-1H-indazol-1-yl)-(651780-33-5)
• EPA Substance Registry System: Ethanone, 1-(6-broMo-1H-indazol-1-yl)-(651780-33-5)

Safety Data

• Hazardous Substances Data: 651780-33-5(Hazardous Substances Data)

Usage

General Description

Ethanone, 1-(6-bromo-1H-indazol-1-yl)- is a chemical compound consisting of an ethanone group attached to a 1-(6-bromo-1H-indazol-1-yl) moiety. Ethanone, 1-(6-broMo-1H-indazol-1-yl)- belongs to the class of indazoles, a group of heterocyclic compounds with a fused ring structure containing both nitrogen and carbon atoms. The bromo substitution at the 6-position of the indazole ring imparts specific chemical and physical properties to the molecule, making it useful in various research and industrial applications. The compound may have potential pharmacological activities that could be explored in drug discovery and development processes. Further studies may be needed to fully understand the properties and potential uses of Ethanone, 1-(6-bromo-1H-indazol-1-yl)-.

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Relevant articles and documents

Protected indazole boronic acid pinacolyl esters: Facile syntheses and studies of reactivities in Suzuki-Miyaura cross-coupling and hydroxydeboronation reactions

The paper describes a rapid and efficient synthesis for the isolation of protected indazolylboronic esters. These compounds were synthesized by reaction between prepared protected haloindazoles and bis(pinacolato)diboron. The effects of solvent, temperature, reaction time, and the nature of halogen atom as well as protecting group were investigated. Additionaly, these compounds reacted either with aryl halides in a Suzuki-Miyaura cross-coupling reaction or with hydrogen peroxide in a hydroxydeboronation reaction showing the potential access to new aryl and hydroxyindazole libraries. Georg Thieme Verlag Stuttgart.

FUSED HETEROARYL DERIVATIVES FOR USE AS P38 KINASE INHIBITORS IN THE TREATMENT OF I.A. RHEUMATOID ARTHRISTIS

Compounds of formula (I): wherein A is a 5-membered heteroaryl ring are inhibitors of p38 kinase and are useful in the treatment of conditions or disease states mediated by p38 kinase activity or mediated by cytokines produced by the activity of p38, such as rheumatoid arthritis.