65243-33-6

Basic information

• Product Name: Cefetamet pivoxyl
• Synonyms: (6R,7R)-7-[[(2Z)-2-(2-AMino-4-thiazolyl)-2-(MethoxyiMino)acetyl]aMino]-3-Methyl -8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid;CefetaMet pivoxyl Hydrochloride;Cefditoren iMpurity 3, CefetaMet Pivoxil;CEFETAMET PIVOXIL HCL;Cefetamet Pivoxil hdyrochloride;CEFERAMETPIVOXYL;cefetamet pivoxyl;(6R,7R)-7-[[(2-Amino-4-thiazolyl)(methoxyimino)acetyl]amino]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid (2,2-dimethyl-1-oxopropoxy)methyl ester
• CAS NO: 65243-33-6
• Molecular Formula: C₂₀H₂₅N₅O₇S₂
• Molecular Weight: 511.58
• Product Categories: Chiral Reagents;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;Sulfur & Selenium Compounds
• Mol File: 65243-33-6.mol
• Article Data: 2

Chemical Properties

• Melting Point: 158-160°C
• Appearance: /
• Density: 1.55 g/cm³
• Refractive Index: 1.684
• Storage Temp.: -20?C Freezer, Under Inert Atmosphere
• PKA: 8.21±0.60(Predicted)
• CAS DataBase Reference: Cefetamet pivoxyl(CAS DataBase Reference)
• NIST Chemistry Reference: Cefetamet pivoxyl(65243-33-6)
• EPA Substance Registry System: Cefetamet pivoxyl(65243-33-6)

Safety Data

• Hazardous Substances Data: 65243-33-6(Hazardous Substances Data)

Usage

Description

Cefetamet pivoxyl is a third-generation cephalosporin antibiotic with potent antibacterial properties. It is a pale yellow solid and is widely used in the medical field for treating various bacterial infections.

Uses

Used in Medical Industry:
Cefetamet pivoxyl is used as an antibiotic for treating a wide range of bacterial infections. Its potent antibacterial activity makes it effective against various types of bacteria, including both Gram-positive and Gram-negative strains. It is particularly useful in treating skin infections, respiratory infections, and urinary tract infections.
Additionally, Cefetamet pivoxyl demonstrates synergistic effects when combined with other antibiotics, enhancing the overall efficacy of the treatment and helping to overcome antibiotic resistance in certain cases.

InChI:InChI=1/C20H25N5O7S2/c1-9-6-33-16-12(23-14(26)11(24-30-5)10-7-34-19(21)22-10)15(27)25(16)13(9)17(28)31-8-32-18(29)20(2,3)4/h7,12,16H,6,8H2,1-5H3,(H2,21,22)(H,23,26)/b24-11-/t12-,16-/m1/s1

Upstream product

• 65243-25-6 sodium 7-[(Z)-2-(2-aminothiazol-4-yl)-2-methoxyiminoacetamido]-3-methyl-ceph-3-em-4-carboxylic acid 
• 53064-79-2 iodomethyl pivaloate 
• 22252-43-3 3-deacetyloxy-7-aminocephalosporanic acid 
• 80756-85-0 (Z)-S-benzo[d]thiazol-2-yl 2-(2-aminothiazol-4-yl)-2-(methoxyimino)ethanethioate 

Downstream Products

• 126747-54-4 (2R,6R,7R)-7-{2-(2-Amino-thiazol-4-yl)-2-[(Z)-methoxyimino]-acetylamino}-3-methyl-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-3-ene-2-carboxylic acid 
• 126617-54-7 (2R,6R,7R)-7-{2-(2-Amino-thiazol-4-yl)-2-[(Z)-methoxyimino]-acetylamino}-3-methyl-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-3-ene-2-carboxylic acid 2,2-dimethyl-propionyloxymethyl ester 
• 65052-63-3 cefetamet 

Relevant articles and documents

IMPROVED PROCESS FOR THE PREPARATION OF CEPHALOSPORIN ANTIBIOTICS

Abstract The present invention more particularly relates to a process for the preparation of cephalosporin antibiotics of the Formula (I) wherein R1 represents hydrogen, trityl, alkyl like CH3, CRaRbCOORc where Ra and Rb independently represent hydrogen or methyl and Rc represents hydrogen or (C1-C6) alkyl; R2 is carboxylate ion or COORd, where Rd represents hydrogen, ester or a counter ion which forms a salt; R3 represents hydrogen, CH3, CH2OCH3, CH2OCOCH3, CH=CH2, Formula (II).