65359-61-7

Basic information

• Product Name: 2,3-Hexadienoic acid, 4-phenyl-, ethyl ester
• CAS NO: 65359-61-7
• Molecular Formula: C14H16O2
• Molecular Weight: 216.28
• Mol File: 65359-61-7.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2,3-Hexadienoic acid, 4-phenyl-, ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3-Hexadienoic acid, 4-phenyl-, ethyl ester(65359-61-7)
• EPA Substance Registry System: 2,3-Hexadienoic acid, 4-phenyl-, ethyl ester(65359-61-7)

Safety Data

• Hazardous Substances Data: 65359-61-7(Hazardous Substances Data)

Upstream product

• 36854-57-6 2-Phenylbutyryl chloride 
• 1530-45-6 (carbethoxymethyl)triphenylphosphonium bromide 
• 623-73-4 diazoacetic acid ethyl ester 
• 20452-67-9 phenylethylketene 
• 867-13-0 diethoxyphosphoryl-acetic acid ethyl ester 

Downstream Products

• 1206896-64-1 5-ethyl-4-fluoro-5-phenyl-2(5H)-furanone 
• 1016988-67-2 C₂₁H₂₂O₃ 
• 1016988-68-3 C₂₁H₂₁ClO₃ 
• 57585-10-1 4-phenyl-2,3-hexadienoic acid methyl ester 
• 36858-91-0 rac.-3-Ethyl-3-phenyl-allencarbonsaeure-⁽¹⁾ 

Relevant articles and documents

Study on the selectivity in the electrophilic monofluorination of 2,3-allenoates with Selectfluor: An efficient synthesis of 4-fluoro-2(5H)-furanones and 3-fluoro-4-oxo-2(E)-alkenoates

Different from the reaction of 2,3-allenoic acids with Selectfluor, 4-fluoro-2(5H)-furanones and (E)-3-fluoro-4-oxo-2-alkenoates were highly selectively generated from 2,4-disubstituted 2,3-allenoates with Selectfluor under different conditions in moderate yields. The reaction of 2, 4, 4-trisubstituted 2,3-allenoates afforded the corresponding 4-fluoro-2(5H)-furanones highly selectively with up to 95% yield under different conditions. The scope of the substrates has been carefully explored. Due to the more readily availability of 2,3-allenoates as compared to 2,3-allenoic acids, new 4-fluoro-2(5H)furanones were prepared. Based on the isolation and characterization of the minor fluorohydroxylation product E-5m, a mechanism has been proposed. The Royal Society of Chemistry 2010.

Olefination of ketenes for the enantioselective synthesis of allenes via an ylide route

Pseudo-C2-symmetric chiral phosphorus ylide is designed and synthesized for the enantioselective preparation of allenic esters, amides, ketone, and nitrile. Up to 92% ee is achieved.