6546-97-0

Basic information

• Product Name: BIS(4-NITROPHENYL) PHOSPHOROCHLORIDATE
• Synonyms: BIS(4-NITROPHENYL) PHOSPHOROCHLORIDATE;Di(4-nitrophenyl)phosphoryl Chloride;Bis(p-nitrophenyl) Phosphorochloridate;Phosphorochloridic Acid Bis(p-nitrophenyl) Ester;p-Nitro-phenol Phosphorochloridate
• CAS NO: 6546-97-0
• Molecular Formula: C₁₂H₈ClN₂O₇P
• Molecular Weight: 358.63
• Product Categories: Aromatics;Intermediates & Fine Chemicals;Pharmaceuticals;Phosphorylating and Phosphitylating Agents
• Mol File: 6546-97-0.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• CAS DataBase Reference: BIS(4-NITROPHENYL) PHOSPHOROCHLORIDATE(CAS DataBase Reference)
• NIST Chemistry Reference: BIS(4-NITROPHENYL) PHOSPHOROCHLORIDATE(6546-97-0)
• EPA Substance Registry System: BIS(4-NITROPHENYL) PHOSPHOROCHLORIDATE(6546-97-0)

Safety Data

• Hazardous Substances Data: 6546-97-0(Hazardous Substances Data)

Usage

Uses

Intermediate in the praparation of chromophoric substrates.

Upstream product

• 645-15-8 Bis(p-nitrophenyl) phosphate 
• 100-02-7 4-nitro-phenol 
• 65463-64-1 para-nitrophenyl phosphonate 
• 2524-64-3 chlorophosphoric acid diphenyl ester 

Downstream Products

• 29845-65-6 (4aR)-6t-(6-amino-purin-9-yl)-3-methyl-2ξ-(4-nitro-phenoxy)-2ξ-oxo-(4ar,7at)-hexahydro-2λ⁵-furo[2,3-e][1,3,2]oxazaphosphinin-7c-ol 
• 96413-67-1 quinolin-8-yl bis(p-nitrophenyl) phosphate 
• 120853-64-7 bis(p-nitrophenyl) 1-oxy-2,2,6,6-tetramethyl-4-piperidinyl phosphoramidate 
• 97280-42-7 N^α--L-alanyl-L-proline tert-butyl ester 
• 97280-43-8 N^α-(bis(4-nitrophenoxy)phosphoryl)-L-alanyl-L-proline 
• 1384863-37-9 C₁₆H₁₆N₃O₉P 

Relevant articles and documents

POLY(PHOSPHOESTERS) FOR DELIVERY OF NUCLEIC ACIDS

Disclosed are polymers comprising the moiety A, which is a moiety of formula I: and pharmaceutically acceptable salts thereof, wherein R, R1, R2, L, n1 and n2 are as defined herein. These polymers are useful for delivering nucleic acids to subject. These polymers and pharmaceutically acceptable compositions comprising such polymers and nucleic acids can be useful for treating various diseases, disorders and conditions.

Synthesis and study of cyclic pronucleotides of 5-fluoro-2′- deoxyuridine

A one-step method for the synthesis of cyclic pronucleotide (cProTide) derivatives of 5-fluoro-2′-deoxyuridine (FdUrd), utilizing a novel phosphoramidating reagent, is described. Stereochemistry at phosphorus was established by NMR studies and modeling. C

Synthesis of Nitroxyl (Aminoxyl) Labeled Probes for Studies of Intracellular Environment by EPR and MRI

Syntheses are delineated for the following three classes of nitroxyl (aminoxyl) labeled active esters: (1) phosphoric acid derivatives containing phenyl and p-nitrophenyl moieties, (2) EDTA and DTPA containing acetoxymethyl and (pivaloyloxy)methyl as protecting groups, and (3) several amino acid derivatives containing the acetoxymethyl group.These compounds are expected to be of interest as potential probes in studies of intracellular environments by ESR spectroscopy and magnetic resonance imaging (MRI).