654655-75-1Relevant articles and documents
PROTEIN CROSSLINKING INHIBITOR AND USE OF THE SAME
-
Page/Page column 36, (2012/11/08)
The present invention relates to: a ketone compound having transglutaminase-inhibiting activity, which is represented by the following Formula 1, 2, or 3: wherein R1 is a substituted or unsubstituted aryl or heterocyclyl group, R2, R3, and R4 are hydrogen atoms, n is 2, X is halogen, R5 and R6 independently represent a hydrogen atom or a substituted or unsubstituted C1-C10 alkyl, aryl, or aralkyl group, wherein R5 and R6 are not hydrogen atoms at the same time, or R5 and R6 may be taken together to form a saturated or unsaturated and substituted or unsubstituted heterocyclyl group containing a nitrogen atom (N); an inhibitor of protein crosslinking comprising the compound; and a composition for preventing or treating a protein-crosslinking causative disease, which comprises the compound or the protein crosslinking inhibitor.
QUINOLINE DERIVATIVES AS ANTIBACTERIAL AGENTS
-
Page/Page column 35, (2010/11/25)
Use of a compound for the manufacture of a medicament for the treatment of a bacterial infection provided that the bacterial infection is other than a Mycobacterial infection, said compound being a compound of Formula (Ia) or (Ib), a pharmaceutically acce
SUBSTITUTED QUINOLINES AND THEIR USE AS MYCOBACTERIAL INHIBITORS
-
Page/Page column 28, (2010/02/13)
The present invention relates to novel substituted quinoline derivatives according to the general formula (Ia) or the general formula (Ib) salts, quaternary amines, stereochemically isomeric forms, tautomeric forms and N--oxide forms thereof, wherein Rsu