6557-86-4

Basic information

• Product Name: Cycloheptanecarbonyl Chloride
• Synonyms: Cycloheptanecarbonyl Chloride
• CAS NO: 6557-86-4
• Molecular Formula: C₈H₁₃ClO
• Molecular Weight: 160.64122
• Mol File: 6557-86-4.mol
• Article Data: 34

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Cycloheptanecarbonyl Chloride(CAS DataBase Reference)
• NIST Chemistry Reference: Cycloheptanecarbonyl Chloride(6557-86-4)
• EPA Substance Registry System: Cycloheptanecarbonyl Chloride(6557-86-4)

Safety Data

• Hazardous Substances Data: 6557-86-4(Hazardous Substances Data)

Usage

General Description

Cycloheptanecarbonyl chloride, also known as cycloheptanecarbonyl chloride or CHCCl, is a chemical compound with the formula C7H11ClO. It is a colorless, slightly yellow liquid with a pungent odor. Cycloheptanecarbonyl chloride is used as an intermediate in organic synthesis, particularly in the manufacture of pharmaceuticals and agrochemicals. It is also used as a reagent for the preparation of various cycloheptanecarbonyl derivatives. Cycloheptanecarbonyl chloride is a highly reactive compound and should be handled with caution due to its corrosive and toxic properties. It is typically stored and transported under controlled conditions to prevent accidents and exposure to the environment.

Upstream product

• 6557-83-1 diethyl cycloheptane-1,1-dicarboxylate 
• 1460-16-8 cycloheptanoic acid 
• 79-37-8 oxalyl dichloride 
• 32315-10-9 bis(trichloromethyl) carbonate 
• 502-41-0 cycloheptanol 

Downstream Products

• 69156-93-0 Cycloheptanecarboxylic acid [2-hydroxy-3-(methyl-phenyl-amino)-propyl]-amide 
• 115732-16-6 N-(cycloheptylcarbonyl)-D-phenylalnine 
• 4277-29-6 cycloheptanecarboxaldehyde 
• 84027-66-7 cycloheptanehydroxamic acid 
• 84027-68-9 Cycloheptanecarboxylic acid cyclohexyl-hydroxy-amide 
• 71608-84-9 2-Cycloheptyl-1-phenyl-1H-quinazolin-4-one 
• 1459-39-8 cycloheptanecarboxamide 
• 177559-11-4 8-Benzyloxy-3-cycloheptylcarbonyl-2-ethylindolizine 
• 316790-79-1 cycloheptanecarboxylic acid (2-bromo-4-methoxy-phenyl)-amide 
• 851980-78-4 cycloheptanecarboxylic acid methyl-phenyl-amide 
• 1026982-71-7 cycloheptanecarboxylic acid [4-(5-nitro-1H-benzoimidazol-2-yl)-phenyl]-amide 
• 959779-79-4 C₂₉H₄₃N₅O₄ 
• 803738-94-5 (1-aza-spiro[2.6]non-1-en-2-yl)-methyl-phenyl-amine 
• 803739-25-5 1',3'-dihydro-1'-methylspiro[cycloheptane-1,3'-[2H]indol]-2'-one 

Relevant articles and documents

Palladium-Catalyzed Migratory Insertion of Carbenes and C-C Cleavage of Cycloalkanecarboxamides

A palladium catalyzed reaction of cycloalkanecarboxamides and diazomalonates or bis(phenylsulfonyl)diazomethane has been developed. The reaction proceeds via carbene migratory insertion and cascade C-C cleavage pathways. Cycloalkanecarboxamides with four to seven membered rings are applicable in the transformation. A series of ring opening products were prepared with moderate yields. The finding provides valuable clues for the development of new reactions involving carbene migratory insertion and the cleavage of unstrained C(sp3)-C(sp3) bonds.

Visible-Light-Assisted Gold-Catalyzed Fluoroarylation of Allenoates

A strategically novel synthetic method for the fluoroarylation of allenic ester was developed that enables the expedient construction of a host of β-fluoroalkyl-containing cinnamate derivatives. The reaction proceeds through visible-light-promoted gold redox catalysis, occurs smoothly under very mild reaction conditions, accommodates a large variety of functional groups, and more importantly allows the incorporation of fluorine and aryl groups with excellent regio- and stereoselectivity. The concomitant activation mode for both the allene motif and the hydrogen fluoride is key for the success of the reaction.

Isoalantolactone derivative, pharmaceutical composition and application thereof

The invention relates to an isoalantolactone derivative, a pharmaceutical composition and application thereof, especially use of the isoalantolactone derivative shown as formula (I) or a salt pharmaceutical compound thereof in preparation of adjuvant drugs treating cancer, a pharmaceutical composition containing a therapeutically effective amount of isoalantolactone derivative (I) or its salt anda pharmaceutically acceptable carrier or a composition with other anticancer drugs.