65577-07-3

Basic information

• Product Name: (-)-1-amino-2-methylpropylphosphonous acid
• CAS NO: 65577-07-3
• Molecular Weight: 137.119
• Mol File: 65577-07-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (-)-1-amino-2-methylpropylphosphonous acid(CAS DataBase Reference)
• NIST Chemistry Reference: (-)-1-amino-2-methylpropylphosphonous acid(65577-07-3)
• EPA Substance Registry System: (-)-1-amino-2-methylpropylphosphonous acid(65577-07-3)

Safety Data

• Hazardous Substances Data: 65577-07-3(Hazardous Substances Data)

Upstream product

• 645-45-4 hydrocinnamic acid chloride 

Downstream Products

• 65577-59-5 <1-<<(phenylmethoxy)carbonyl>amino>-2-methylpropyl>phosphinic acid 
• 18108-24-2 (-)-1-amino-2-methylpropylphosphonic acid 
• 18108-24-2 (1-amino-2-methylpropyl)phosphonic acid 

Relevant articles and documents

Phosphonic acid derivatives having carboxypeptidase b inhibitory activity

A compound represented by the following general formula (I) and a pharmacologically acceptable salt thereof: wherein R1represents hydrogen atom, an alkyl group, a substituted alkyl group and the like; R2and R3represent hydrogen atom, an alkyl group, a substituted alkyl group, an alkoxyl group and the like; X represents —CH2—, —O—, or —NH—; A represents the following group (II): [in which R7and R8represent hydrogen atom, an alkyl group, an acyl group, an alkoxycarbonyl group and the like; R9and R10represents hydrogen atom, a halogen atom, hydroxyl group, phenyl group, an alkyl group and the like] and the like; and E represents hydrogen atom and the like, which has inhibitory activity against carboxypeptidase B and is useful for therapeutic and/or preventive treatment of a thrombotic disease.