65738-69-4 Usage
Description
2-[(ADAMANTAN-1-YLMETHYL)-AMINO]-ETHANOL, commonly known as memantine, is a pharmaceutical compound derived from the chemical adamantane. It features a unique structure that selectively targets specific receptors in the brain, particularly those for the neurotransmitter glutamate, which is implicated in the progression of Alzheimer's disease. Memantine's ability to block these receptors helps to mitigate the symptoms of the disease and enhance cognitive function, making it a valuable treatment option for Alzheimer's patients.
Uses
Used in Pharmaceutical Industry:
2-[(ADAMANTAN-1-YLMETHYL)-AMINO]-ETHANOL is used as a medication for the treatment of Alzheimer's disease. It functions by selectively blocking the receptors for the neurotransmitter glutamate, which is believed to contribute to the disease's progression. This action helps to alleviate the symptoms of Alzheimer's and improve cognitive function in affected individuals.
As a treatment for Alzheimer's disease, memantine is generally well-tolerated with minimal side effects, offering a beneficial option for managing the cognitive decline associated with this condition. Its selective targeting of specific receptors also contributes to its effectiveness and safety profile, distinguishing it as a valuable component in the therapeutic arsenal against Alzheimer's.
Check Digit Verification of cas no
The CAS Registry Mumber 65738-69-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,5,7,3 and 8 respectively; the second part has 2 digits, 6 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 65738-69:
(7*6)+(6*5)+(5*7)+(4*3)+(3*8)+(2*6)+(1*9)=164
164 % 10 = 4
So 65738-69-4 is a valid CAS Registry Number.
InChI:InChI=1/C13H23NO/c15-2-1-14-9-13-6-10-3-11(7-13)5-12(4-10)8-13/h10-12,14-15H,1-9H2
65738-69-4Relevant articles and documents
Novel antitumor adamantane-azole gold(I) complexes as potential inhibitors of thioredoxin reductase
Garcia, Adriana,Machado, Rafael Carvalhaes,Grazul, Richard Michael,Lopes, Miriam Teresa Paz,Corrêa, Charlane Cimini,Dos Santos, Hélio F.,De Almeida, Mauro Vieira,Silva, Heveline
, p. 275 - 292 (2016/04/05)
Gold complexes that could act as antitumor agents have attracted great attention. Heterocyclic compounds and their metal complexes display a broad spectrum of pharmacological properties. The present study reports the preparation and characterization of fo
DERIVATIVES OF ADAMANTANE. I. 2-HYDROXYETHYLAMINO DERIVATIVES OF ADAMANTANE
Plakhotnik, V. M.,Kovtun, V. Yu.,Krasutskii, P. A.,Novikova, M. I.,Prokhorov, A. B.,et al.
, p. 1287 - 1290 (2007/10/02)
The reaction of 1-bromoadamantane with hydroxyalkylamines leads to the preferential formation of 1-(aminoalkoxy)adamantanes.The 2-hydroxyethylamino derivatives of the adamantane series were obtained by the reaction of ethylene oxide with the corresponding amines.
