6575-10-6

Basic information

• Product Name: 2-CHLORO-6-METHOXYBENZONITRILE
• Synonyms: 2-CHLORO-6-METHOXYBENZONITRILE;Benzonitrile, 2-chloro-6-methoxy-;2-Chloro-6-methoxybenzonitrile,97%;2-Methoxy-6-chlorobenzonitrile;6-Chloro-o-anisonitrile
• CAS NO: 6575-10-6
• Molecular Formula: C₈H₆ClNO
• Molecular Weight: 167.59
• EINECS: 229-500-9
• Product Categories: Aromatics Compounds;Aromatics
• Mol File: 6575-10-6.mol
• Article Data: 4

Chemical Properties

• Melting Point: 98-100°C
• Boiling Point: 294.7 °C at 760 mmHg
• Flash Point: 132 °C
• Appearance: /
• Density: 1.25 g/cm³
• Storage Temp.: -20?C Freezer
• Solubility: Chloroform, Ethyl Acetate
• CAS DataBase Reference: 2-CHLORO-6-METHOXYBENZONITRILE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-CHLORO-6-METHOXYBENZONITRILE(6575-10-6)
• EPA Substance Registry System: 2-CHLORO-6-METHOXYBENZONITRILE(6575-10-6)

Safety Data

• Hazard Codes: Xn
• Statements: 22
• Hazardous Substances Data: 6575-10-6(Hazardous Substances Data)

Usage

Description

2-Chloro-6-methoxybenzonitrile, with the CAS number 6575-10-6, is an organic compound characterized by its white needle-like appearance. It is primarily utilized in the field of organic synthesis, playing a crucial role in the creation of various chemical compounds.

Uses

Used in Organic Synthesis:
2-Chloro-6-methoxybenzonitrile is used as a key intermediate in the synthesis of various organic compounds. Its unique chemical structure allows it to participate in a range of reactions, making it a valuable asset in the development of new molecules with potential applications in various industries.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 2-Chloro-6-methoxybenzonitrile is used as a building block for the synthesis of various pharmaceutical compounds. Its versatility in organic synthesis enables the creation of new drugs with potential therapeutic benefits.
Used in Chemical Research:
2-Chloro-6-methoxybenzonitrile is also employed in chemical research, where it serves as a model compound for studying various reaction mechanisms and exploring new synthetic pathways. This contributes to the advancement of knowledge in the field of chemistry and the development of innovative chemical processes.
Used in Agrochemical Industry:
In the agrochemical industry, 2-Chloro-6-methoxybenzonitrile is used as a starting material for the synthesis of various agrochemicals, such as pesticides and herbicides. Its application in this industry helps in the development of more effective and environmentally friendly solutions for agricultural challenges.
Used in Dye and Pigment Industry:
2-Chloro-6-methoxybenzonitrile is also utilized in the dye and pigment industry for the synthesis of various colorants. Its unique chemical properties enable the creation of new dyes and pigments with improved performance characteristics, such as enhanced color strength and stability.

InChI:InChI=1S/C8H6ClNO/c1-11-8-4-2-3-7(9)6(8)5-10/h2-4H,1H3

Upstream product

• 158966-62-2 6-chloro-o-anisidine 
• 5472-99-1 3-chloro-2-nitroanisole 
• 668-45-1 2-chloro-6-fluorobenzonitrile 
• 89999-90-6 3-chloro-2-cyanophenol 
• 74-88-4 methyl iodide 
• 124-41-4 sodium methylate 

Downstream Products

• 3260-89-7 2-chloro-6-methoxybenzoic acid 
• 116617-00-6 3-Amino-1-cyano-1-(4-fluoro-phenyl)-4-methoxy-1H-indene-2-carboxylic acid methyl ester 
• 65582-55-0 1,7-Dihydroxy-10-methyl-9-acridon 
• 112649-95-3 1,7-Dihydroxy-9-acridon 
• 112649-77-1 N-(4'-Methoxyphenyl)-6-methoxyanthranilsaeure 
• 107485-43-8 C₈H₈ClNO₂ 
• 1354928-51-0 C₁₇H₁₁ClO₄ 
• 1354928-57-6 C₁₇H₁₁ClO₄ 
• 55736-04-4 6’-chloro-2’-hydroxyacetophenone 
• 881883-32-5 1-(2-Chloro-6-methoxy-phenyl)-ethanone 
• 1638631-82-9 2-methoxy-6-(3-methoxy-4-methylphenylamino)benzonitrile 
• 104778-01-0 Murrayaline-A 
• 139726-42-4 murrayaline B 
• 1638631-87-4 7-benzyloxy-2-methoxy-6-methylcarbazole-1-carbonitrile 

Relevant articles and documents

Exploiting Imine Photochemistry for Masked N-Centered Radical Reactivity

This report details the development of a masked N-centered radical strategy that harvests the energy of light to drive the conversion of cyclopropylimines to 1-aminonorbornanes. This process employs the N-centered radical character of a photoexcited imine to facilitate the homolytic fragmentation of the cyclopropane ring and the subsequent radical cyclization sequence that forms two new C?C bonds en route to the norbornane core. Achieving bond-forming reactivity as a function of the N-centered radical character of an excited state Schiff base is unique, requiring only violet light in this instance. This methodology operates in continuous flow, enhancing the potential to translate beyond the academic sector. The operational simplicity of this photochemical process and the structural novelty of the (hetero)aryl-fused 1-aminonorbornane products are anticipated to provide a valuable addition to discovery efforts in pharmaceutical and agrochemical industries.

Palladium(II)-catalyzed synthesis of the formylcarbazole alkaloids murrayaline A-C, 7-methoxymukonal, and 7-methoxy-o-methylmukonal

We describe the synthesis of the naturally occurring 2,7-dioxygenated formylcarbazole alkaloids 7-methoxymukonal, 7-methoxy-O-methylmukonal, and the murrayalines A-C. The carbazole framework was constructed by a Buchwald-Hartwig amination and a subsequent palladium(II)-catalyzed oxidative cyclization. We describe the synthesis of the naturally occurring 2,7-dioxygenated formylcarbazole alkaloids 7-methoxymukonal, 7-methoxy-O-methylmukonal, and the murrayalines A-C. The carbazole framework was constructed by a Buchwald-Hartwig amination and a subsequent palladium(II)-catalyzed oxidative cyclization. Copyright