66052-32-2

Basic information

• Product Name: methyl 2,5-dimethyl-2-vinylhex-4-enoate
• Synonyms: methyl 2,5-dimethyl-2-vinylhex-4-enoate;2-Ethenyl-2,5-dimethyl-4-hexenoic acid methyl ester;4-Hexenoic acid, 2-ethenyl-2,5-dimethyl-, methyl ester;Einecs 266-092-1;Methyl 2,5-dimethyl-2-vinyl-4-hexenoate
• CAS NO: 66052-32-2
• Molecular Formula: C₁₁H₁₈O₂
• Molecular Weight: 182.25942
• EINECS: 266-092-1
• Mol File: 66052-32-2.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 210.9°Cat760mmHg
• Flash Point: 67.6°C
• Appearance: /
• Density: 0.901g/cm³
• Vapor Pressure: 0.188mmHg at 25°C
• Refractive Index: 1.45
• CAS DataBase Reference: methyl 2,5-dimethyl-2-vinylhex-4-enoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 2,5-dimethyl-2-vinylhex-4-enoate(66052-32-2)
• EPA Substance Registry System: methyl 2,5-dimethyl-2-vinylhex-4-enoate(66052-32-2)

Safety Data

• Hazardous Substances Data: 66052-32-2(Hazardous Substances Data)

Usage

InChI:InChI=1/C11H18O2/c1-6-11(4,10(12)13-5)8-7-9(2)3/h6-7H,1,8H2,2-5H3

Upstream product

• 186581-53-3 diazomethane 
• 80-59-1 Tiglic acid 
• 870-63-3 prenyl bromide 

Relevant articles and documents

Synthesis of isoprenoid 1,5-dienes

Aliphatic acids containing an isoprenoid 1,5-diene moiety are prepared in high yields by the selective gamma alkylation of α,β-unsaturated acids with allylic electrophiles. The gamma-regioselectivity of the alkylation is controlled by the use of the dicopper(I) dienolates prepared from the α,β-unsaturated acids. The method offers a particularly facile means for synthesizing isoprenoid 1,5-diene natural products such as farnesoic acid by alkylation of senecioic acid with geranyl bromide; geranoic acid by alkylation of senecioic acid with 3,3-dimethallyl bromide; and dl-lanceol by alkylation of tiglic acid with an allylic bromide derived from dl-limonene. Such products find use in the synthesis of insect pheremones, insect juvenile hormones, and components of perfumes.