66056-40-4 Usage
Description
2-[2,4-Bis(benzyloxy)phenyl]acetic Acid is a chemical compound with the molecular formula C23H22O4. It is a derivative of acetic acid and contains two benzyl ether groups attached to a phenyl ring. 2-[2,4-Bis(benzyloxy)phenyl]acetic Acid is known for its versatile structure and reactivity, making it a valuable building block for the creation of more complex molecules. Its properties may make it useful for a variety of research purposes, particularly in the synthesis of pharmaceuticals and organic materials.
Uses
Used in Pharmaceutical Synthesis:
2-[2,4-Bis(benzyloxy)phenyl]acetic Acid is used as a key intermediate in the synthesis of pharmaceuticals for its ability to contribute to the development of new drugs. Its unique structure allows for the creation of complex molecules that can target specific biological pathways, potentially leading to more effective treatments.
Used in Organic Material Synthesis:
In the field of organic materials, 2-[2,4-Bis(benzyloxy)phenyl]acetic Acid is used as a building block for the synthesis of various organic compounds. Its presence in these materials can enhance their properties, such as stability, reactivity, or specific functional groups, making them suitable for a range of applications.
Used in Organic Chemistry Research:
2-[2,4-Bis(benzyloxy)phenyl]acetic Acid is utilized as a research compound in organic chemistry. Its reactivity and structural features make it an interesting subject for studying reaction mechanisms, exploring new synthetic routes, and understanding the properties of related compounds.
Used in Drug Discovery:
In the realm of drug discovery, 2-[2,4-Bis(benzyloxy)phenyl]acetic Acid is used as a starting material or a component in the design of novel drug candidates. Its potential applications in this field highlight its importance in the development of new therapeutic agents that can address unmet medical needs.
Overall, 2-[2,4-Bis(benzyloxy)phenyl]acetic Acid is a versatile and potentially valuable chemical compound with a wide range of potential applications in various fields of science and industry, including pharmaceuticals, organic materials, organic chemistry research, and drug discovery.
Check Digit Verification of cas no
The CAS Registry Mumber 66056-40-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,6,0,5 and 6 respectively; the second part has 2 digits, 4 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 66056-40:
(7*6)+(6*6)+(5*0)+(4*5)+(3*6)+(2*4)+(1*0)=124
124 % 10 = 4
So 66056-40-4 is a valid CAS Registry Number.
66056-40-4Relevant articles and documents
The total large-scale synthesis of argiopine
Formanovsky,Popova,Mikhura
experimental part, p. 752 - 758 (2010/07/15)
The total large-scale synthesis of a natural toxin argiopine, a polymethylenepolyamine derivative, was developed. It consisted of 26 stages and included three key block schemes. Most of the stages proceeded quantitatively, which excluded the necessity of using the chromatographic separation of intermediates.
Total syntheses of spidamine and joramine, polyamine toxins from the joro spider, Nephila clavata
Chiba, Tadashige,Akizawa, Toshifumi,Matsukawa, Motomi,Nishi, Masatoshi,Kawai, Nobufumi,Yoshioka, Masanori
, p. 972 - 979 (2007/10/03)
In order to confirm the structures of spidamine and joramine, identified from the venom of a spider (nephila clavata), we convergently synthesized both compounds, which have a common side chain of N-(L-asparaginyl)-N'-(3- aminopropyl-β-alanyl)-1,5-pentanediamine. A synthon of the common side chain was synthesized by starting with n-propanolamine which was converted to 7- azido-N-benzyloxycarbonyl-4-azaheptanoic acid N-hydroxysuccinimidyl ester. The ester was coupled with tert-butyloxycarbonyl-L-asparaginyl-1,5- pentanediamine to give the synthon of the common side chain. In the final synthesis of spidamine, the synthon of the common side chain was reacted with 2,4-dibenzyloxyphenylacetic acid N-hydroxysuccinimidyl ester, obtained by Willgerodt-kindler reaction of 2,4-dihydroxyacetophenone. The protected spidamine was catalytically hydrogenated to remove protective groups, affording spidamine itself in 13% yield from n-propanolamine. In the final synthesis of joramine, the synthon of the common side chain was reacted with 4-benzyloxyphenyl acetic acid N-hydroxysuccinimidyl ester. The protected joramine was also catalytically hydrogenated to produce joramine itself in 11% yield. The conformations of both synthesized compounds were analyzed by 1H-NMR and 13C-NMR. Their blocking activities on glutamate receptors were examined using lobster neuromuscular synapses.
Synthesis and assay of hybrid analogs of argiotoxin-636 and philanthoxin-433: Glutamate receptor antagonists
Choi,Nakanishi,Usherwood
, p. 5777 - 5790 (2007/10/02)
The synthesis of the non-competitive glutamate receptor antagonist, argiotoxin-636 is described. Furthermore, synthetic routes are presented for the preparation of structural analogs including argiotoxin-philanthotoxin hybrids. Biological activities on gl
