66158-96-1 Usage
Description
2,3-Dihydro-1-benzofuran-2-ylmethanol, also known as 2,3-dihydrobenzofuran-2-methanol, is an organic compound with the chemical formula C9H10O2. It is a colorless oil at room temperature and serves as a reactant in the synthesis of various compounds, particularly those related to thromboxane A2 agonist indane derivatives.
Uses
Used in Pharmaceutical Industry:
2,3-Dihydro-1-benzofuran-2-ylmethanol is used as a reactant for the preparation of thromboxane A2 agonist indane derivatives. These derivatives have potential applications in the development of medications targeting thromboxane A2 receptors, which play a role in various physiological processes, including blood clotting and inflammation.
Used in Chemical Synthesis:
As a versatile reactant, 2,3-dihydro-1-benzofuran-2-ylmethanol can be employed in the synthesis of a range of chemical compounds, contributing to the development of new materials and products across various industries. Its unique chemical structure allows for further functionalization and modification, making it a valuable building block in organic chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 66158-96-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,6,1,5 and 8 respectively; the second part has 2 digits, 9 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 66158-96:
(7*6)+(6*6)+(5*1)+(4*5)+(3*8)+(2*9)+(1*6)=151
151 % 10 = 1
So 66158-96-1 is a valid CAS Registry Number.
InChI:InChI=1/C9H10O2/c10-6-8-5-7-3-1-2-4-9(7)11-8/h1-4,8,10H,5-6H2
66158-96-1Relevant articles and documents
Gold-catalysed activation of epoxides: Application in the synthesis of bicyclic ketals
Balamurugan, Rengarajan,Kothapalli, Raveendra Babu,Thota, Ganesh Kumar
experimental part, p. 1557 - 1569 (2011/04/25)
Gold-catalysed generation of diol equivalents from epoxides and their intramolecular reaction with Ca≡C bonds to generate bicyclic ketals is presented. This reaction essentially involves the formation of an acetonide, which subsequently cyclises on the alkyne intramolecularly under gold catalysis conditions. This method could be extended to make optically pure bicyclic ketals. Deuterium incorporation experiments were carried out to ascertain the mechanism of the reaction. Sequential activation of epoxide and alkyne moieties by a gold catalyst in acetone as solvent has been achieved. This strategyhas been employed to synthesise bicyclic ketals from epoxy alkynes. Copyright
