6623-93-4

Basic information

• Product Name: 4-(1-METHYL-1-PHENYL-ETHYL)-ANISOLE
• Synonyms: 4-(1-METHYL-1-PHENYL-ETHYL)-ANISOLE;1-Methoxy-4-(2-phenylpropan-2-yl)benzene
• CAS NO: 6623-93-4
• Molecular Formula: C₁₆H₁₈O
• Molecular Weight: 226.31352
• Mol File: 6623-93-4.mol
• Article Data: 16

Chemical Properties

• Boiling Point: 323.5°C at 760 mmHg
• Flash Point: 127.3°C
• Appearance: /
• Density: 0.998g/cm³
• Vapor Pressure: 0.000492mmHg at 25°C
• Refractive Index: 1.539
• CAS DataBase Reference: 4-(1-METHYL-1-PHENYL-ETHYL)-ANISOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(1-METHYL-1-PHENYL-ETHYL)-ANISOLE(6623-93-4)
• EPA Substance Registry System: 4-(1-METHYL-1-PHENYL-ETHYL)-ANISOLE(6623-93-4)

Safety Data

• Hazardous Substances Data: 6623-93-4(Hazardous Substances Data)

Usage

General Description

4-(1-methyl-1-phenyl-ethyl)-anisole, also known as methylphenidate, is a central nervous system stimulant that is used in the treatment of attention deficit hyperactivity disorder (ADHD) and narcolepsy. It works by increasing the activity of certain neurotransmitters in the brain, leading to improved focus and attention. Methylphenidate is available in both immediate-release and extended-release formulations and is typically taken orally. It has the potential for abuse and dependence, and its use should be closely monitored by a healthcare professional. Common side effects of methylphenidate include insomnia, decreased appetite, and increased heart rate.

InChI:InChI=1/C16H18O/c1-16(2,13-7-5-4-6-8-13)14-9-11-15(17-3)12-10-14/h4-12H,1-3H3

Upstream product

• 934-53-2 cumenyl chloride 
• 13139-86-1 4-methoxyphenyl magnesium bromide 
• 599-64-4 p-cumylphenol 
• 77-78-1 dimethyl sulfate 
• 4333-75-9 1-(4-methoxyphenyl)-1-phenylethene 
• 100-66-3 methoxybenzene 
• 617-94-7 1-methyl-1-phenylethyl alcohol 
• 98-83-9 isopropenylbenzene 
• 80-15-9 Cumene hydroperoxide 
• 74-88-4 methyl iodide 
• 5720-07-0 4-methoxyphenylboronic acid 

Downstream Products

• 599-64-4 p-cumylphenol 
• 70757-61-8 [4-(1-methyl-1-phenyl-ethyl)-phenoxy]-acetic acid 

Relevant articles and documents

Ligand-Enabled Nickel-Catalyzed Redox-Relay Migratory Hydroarylation of Alkenes with Arylborons

A redox-relay migratory hydroarylation of isomeric mixtures of olefins with arylboronic acids catalyzed by nickel complexes bearing diamine ligands is described. A range of structurally diverse 1,1-diarylalkanes, including those containing a 1,1-diarylated quaternary carbon, were obtained in excellent yields and with high regioselectivity. Preliminary experimental evidence supports the proposed non-dissociated chainwalking of aryl-nickel(II)-hydride species along the alkyl chain of alkenes before selective reductive elimination at a benzylic position. A catalyst loading as low as 0.5 mol % proved to be sufficient in large-scale synthesis while retaining high reactivity, highlighting the practical value of this transformation.

A transition metal complex compound, and the compound of the catalyst and a catalyst for large amt. pentavelent carried out in the presence of an olefin multimer manufacturing method

PROBLEM TO BE SOLVED: To provide a transition metal complex compound, to provide an olefin polymerizing catalyst, containing the compound, and having excellent activity, and to provide a method for producing the olefin polymer which is carried out in the presence of the catalyst.SOLUTION: There is provided the transition metal complex compound of compound 3, e.g. of chemical formula; and the olefin polymerizing catalyst including following components (A) and (B): (A) the transition metal compound; and (B) at least one compound selected from the group consisting of (B-1) an organometallic compound, (B-2) an organoaluminumoxy compound, and (B-3) a compound reactive with the transition metal compound (A), and forming an ion pair.

Cationic Iron(III) porphyrin catalyzed dehydrative friedel-crafts reaction of alcohols with arenes

Alcohols react with arenes in the presence of cationic iron(III) porphyrin catalyst. The reaction involves the formation of the C-C bond via dehydration, which is formal Lewis acid catalyzed Friedel-Crafts reaction. Georg Thieme Verlag Stuttgart, New York.