66232-34-6

Basic information

• Product Name: 4-tert-Butylsalicylaldehyde
• Synonyms: BENZALDEHYDE, 4-(1,1-DIMETHYLETHYL)-2-HYDROXY-;4-TERT-BUTYLSALICYLALDEHYDE;4-TERT-BUTYL-2-HYDROXYBENZALDEHYDE;4-tert-Butylsalicylaldehy
• CAS NO: 66232-34-6
• Molecular Formula: C₁₁H₁₄O₂
• Molecular Weight: 178.23
• EINECS: 1533716-785-6
• Product Categories: Benzaldehyde
• Mol File: 66232-34-6.mol
• Article Data: 10

Chemical Properties

• Boiling Point: 262.916 °C at 760 mmHg
• Flash Point: 109.169 °C
• Appearance: /
• Density: 1.072 g/cm³
• Vapor Pressure: 0.007mmHg at 25°C
• Refractive Index: 1.554
• PKA: 8.29±0.10(Predicted)
• CAS DataBase Reference: 4-tert-Butylsalicylaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 4-tert-Butylsalicylaldehyde(66232-34-6)
• EPA Substance Registry System: 4-tert-Butylsalicylaldehyde(66232-34-6)

Safety Data

• Hazard Codes: Xi
• Hazardous Substances Data: 66232-34-6(Hazardous Substances Data)

Usage

Uses

4-tert-Butyl-2-hydroxybenzaldehyde is a useful chemical in organic synthesis.

InChI:InChI=1/C11H14O2/c1-11(2,3)9-5-4-8(7-12)10(13)6-9/h4-7,13H,1-3H3

Upstream product

• 50-00-0 formaldehyd 
• 585-34-2 3-tert-butylphenyol 
• 100-97-0 hexamethylenetetramine 
• 939-97-9 4-tert-Butylbenzaldehyde 

Downstream Products

• 174822-06-1 2-hydroxymethyl-5-t-butylphenol 
• 639069-51-5 5-tert-butyl-2-[(propylamino)methyl]phenol 
• 856252-78-3 trifluoro-methanesulfonic acid 5-tert-butyl-2-formyl-phenyl ester 
• 5781-02-2 5-(tert-butyl)-2-methylphenol 
• 367965-70-6 3-(bromomethyl)-5-(tert-butyl)-2-hydroxybenzaldehyde 
• 919109-50-5 3,3′-(1,4-piperazine-bis-(methylene)-bis-(5-tert-butyl)-2-hydroxybenzaldehyde) 

Relevant articles and documents

Phosphine-Catalyzed [3+2] Annulation of β-Sulfonamido-Substituted Enones with Sulfamate-Derived Cyclic Imines

Phosphine-catalyzed [3+2] annulation of β-sulfonamido-substituted enones and sulfamate-derived cyclic imines has been developed, giving a series of imidazoline derivatives in moderate to excellent yields with good to excellent diastereoselectivities. A scale-up reaction worked well under mild reaction conditions. A possible mechanism was proposed on the basis of the results obtained.

Aldehyde-Assisted Ruthenium(II)-Catalyzed C-H Oxygenations

Versatile ruthenium(II) complexes allow for site-selective C-H oxygenations with weakly-coordinating aldehydes. The challenging C-H functionalizations proceed with high chemoselectivity by rate-determining C-H metalation. The new method features an ample substrate scope, which sets the stage for the step-economical preparation of various bioactive heterocycles.

AMINOALKYLPHENOLS, METHODS OF USING AND MAKING THE SAME

The present invention relates to Mannich base antimalarial aminoalkylphenol compounds and their use against protozoa of the genus Plasmodium, particularly emerging strains of drug-resistant Plasmodia. This invention further relates to compositions contain