6639-43-6Relevant articles and documents
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Budde,Potempa
, p. 258 (1952)
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I2/Li2CO3-promoted cyanation of diarylalcohols through a dual activation process
Hu, Liangzhen,Hussain, Muhammad Ijaz,Deng, Qingfu,Liu, Qing,Feng, Yangyang,Zhang, Xiaohui,Xiong, Yan
supporting information, p. 308 - 314 (2018/12/11)
One-step base promoted strategy for cyanation of α,α-diaryl alcohols has been developed under mild and transition metal-free conditions. This method provides a straightforward and facile way towards the synthesis of β,γ-unsaturated nitriles and α-phenylnitiriles from α-vinyl carbinols and α,α-diaryl methanols, respectively, up to 99% yield. Moreover, various azides and ethers could also be accessed from their respective nucleophiles under standard reaction conditions.
Hydride Reduction by a Sodium Hydride-Iodide Composite
Too, Pei Chui,Chan, Guo Hao,Tnay, Ya Lin,Hirao, Hajime,Chiba, Shunsuke
supporting information, p. 3719 - 3723 (2016/03/26)
Sodium hydride (NaH) is widely used as a Br?nsted base in chemical synthesis and reacts with various Br?nsted acids, whereas it rarely behaves as a reducing reagent through delivery of the hydride to polar π electrophiles. This study presents a series of reduction reactions of nitriles, amides, and imines as enabled by NaH in the presence of LiI or NaI. This remarkably simple protocol endows NaH with unprecedented and unique hydride-donor chemical reactivity.
Efficient assembly of α-aryl and α-vinyl nitriles via iron-catalyzed ether bond activation
Fan, Xiaohui,Guo, Kun,Guan, Yong-Hong,Fu, Lin-An,Cui, Xiao-Meng,Lv, Hao,Zhu, Hong-Bo
supporting information, p. 1068 - 1071 (2014/02/14)
A novel and practical method for the synthesis of diverse α-aryl and α-vinyl nitriles was developed via an iron-catalyzed sp3 C-O ether bond cleavage with C-C bond formation in the reaction of π-activated ethers with TMSCN.