6641-02-7 Usage
General Description
2,4-Dichloro-6-(hydroxymethyl)phenol, also known as triclosan, is a synthetic chemical with antimicrobial properties that is commonly used in personal care products, household goods, and medical supplies. It works by disrupting the cell membranes of bacteria and other microorganisms, effectively killing them. However, concerns have been raised about its potential contribution to antibiotic resistance and negative impacts on human health and the environment. Triclosan has been linked to hormone disruption, development of resistant bacteria, and environmental contamination. Due to these concerns, its use in consumer products has been restricted in some countries, and alternatives are being sought.
Check Digit Verification of cas no
The CAS Registry Mumber 6641-02-7 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,6,4 and 1 respectively; the second part has 2 digits, 0 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 6641-02:
(6*6)+(5*6)+(4*4)+(3*1)+(2*0)+(1*2)=87
87 % 10 = 7
So 6641-02-7 is a valid CAS Registry Number.
InChI:InChI=1/C7H6Cl2O2/c8-5-1-4(3-10)7(11)6(9)2-5/h1-2,10-11H,3H2
6641-02-7Relevant articles and documents
Asymmetric Retro-Claisen Reaction by Synergistic Chiral Primary Amine/Palladium Catalysis
Han, Yanfang,Zhang, Long,Luo, Sanzhong
supporting information, p. 7258 - 7261 (2019/10/02)
We described herein a chiral primary amine/palladium catalyzed asymmetric retro-Claisen reaction of β-diketones with salicylic carbonates. A series of chiral α-alkylated ketones and macrolides were obtained with good yields and excellent enantioselectivities upon a sequence of decarboxylative benzylation, retro-Claisen cleavage, and enamine protonation. This strategy features broad substrate scope, mild conditions, as well as high atom economy with salicylic carbonates as the o-quinone methide precursors.
