666234-81-7 Usage
Description
(R)-3-(Dimethylamino)-1,2-propanediol, also known as Ropivacaine, is a chiral local anesthetic medication derived from the amino alcohol 1,2-propanediol. It possesses a unique structure that allows it to selectively block nerve signals, providing temporary numbness and relief from pain. Ropivacaine is characterized by its longer duration of action and reduced systemic toxicity compared to other local anesthetics, making it a preferred choice for various medical applications.
Uses
Used in Surgical Procedures:
Ropivacaine is used as a local anesthetic for surgical procedures, providing effective pain management and ensuring patient comfort during and after the operation. Its longer duration of action allows for extended periods of pain relief, reducing the need for additional anesthetic interventions.
Used in Epidural Anesthesia for Labor and Delivery:
Ropivacaine is utilized as an epidural anesthetic during labor and delivery, offering pain relief to the mother while minimizing the risk of motor block and other side effects. Its selective nerve blocking properties enable effective pain management without compromising the mother's ability to move and participate in the birthing process.
Used in Post-operative Pain Control:
Ropivacaine is employed for post-operative pain control, helping patients manage pain and recover more comfortably after surgery. Its extended duration of action and reduced systemic toxicity make it an ideal choice for prolonged pain relief, reducing the need for additional analgesic medications and potential side effects.
It is crucial to note that ropivacaine should be used under the supervision of a healthcare professional to ensure safe and effective pain management. Improper use can lead to serious side effects and complications.
Check Digit Verification of cas no
The CAS Registry Mumber 666234-81-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,6,6,2,3 and 4 respectively; the second part has 2 digits, 8 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 666234-81:
(8*6)+(7*6)+(6*6)+(5*2)+(4*3)+(3*4)+(2*8)+(1*1)=177
177 % 10 = 7
So 666234-81-7 is a valid CAS Registry Number.
666234-81-7Relevant articles and documents
Asymmetric Synthesis of Dialkyloxy-3-alkylammonium Cationic Lipids
Hurley, Christopher A.,Wong, John B.,Hailes, Helen C.,Tabor, Alethea B.
, p. 980 - 983 (2004)
The cationic diether-linked cytofectin DOTMA (available commercially as a mixture, Lipofectin comprised of DOTMA:DOPE, 1:1) and analogues including DIMRIE and DORIE are frequently used for in vitro and in vivo transfections. Despite this wide usage direct synthetic routes to the optical isomers have received little attention to date. Here we describe strategies to synthesize enantiomers of DOTMA and analogues, including an extremely concise procedure to the trimethylammonium salts. One strategy utilized N-protection, as the imine, with concomitant ether formation and deprotection during the workup. Methylation of the 1-amino-2,3-dialkyloxypropane then generated the trimethylammonium cationic lipids directly. This methodology was extended to synthesize a novel headgroup functionalized lipid. A second route was also developed using an alternative chiral synthon.
