66702-75-8

Basic information

• Product Name: Ethanone, 2-(nitrooxy)-1-phenyl-
• CAS NO: 66702-75-8
• Molecular Formula: C8H7NO4
• Molecular Weight: 181.148
• Mol File: 66702-75-8.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Ethanone, 2-(nitrooxy)-1-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Ethanone, 2-(nitrooxy)-1-phenyl-(66702-75-8)
• EPA Substance Registry System: Ethanone, 2-(nitrooxy)-1-phenyl-(66702-75-8)

Safety Data

• Hazardous Substances Data: 66702-75-8(Hazardous Substances Data)

Upstream product

• 70-11-1 α-bromoacetophenone 
• 98-86-2 acetophenone 
• 4636-16-2 iodoacetophenone 
• 67-56-1 methanol 
• 13684-98-5 2-methoxy-2-phenylethyl iodide 
• 4747-13-1 α-methoxystyrene 
• 100-42-5 styrene 

Downstream Products

• 10562-42-2 3,3-dichloro-1-phenyl-propenone 
• 1074-12-0 phenylglyoxal hydrate 

Relevant articles and documents

Synthesis of α-Functionalized Trichloromethylcarbinols

A new series of α-functionalized trichloromethylcarbinols have been synthesized from corresponding α-halomethyl ketones, esters, and amides in 48-78% overall yields. Reactivity of nitrates obtained in the first step was dependent on the electron-withdrawi

Conversion of Aromatic Ketones into α-Arylalkanoic Acids. Oxidation by Thallium(III) and by Halogens

The mechanism by which thallium (III) nitrate oxidises aromatic ketones to α-arylalkanoic acids has been investigated and the role of additives in the system elucidated.It is found that in the absence of additives an organothallium intermediate, most probably the phenacylthallium species BzCH2Tl(NO3)2, persists and that the key to an efficient rearrangement is the ready conversion of this compound into its acetal.Thallium(III) is shown not to be a unique reagent for the oxidation.Other oxidants capable of acting initially as an electrophile and then as a leaving group are equally effective, provided that formation of an acetal is possible.Iodine-silver nitrate in particular offers considerable advantages as reagent over thallium(III).Higher specificity is achieved, unwanted side-reactions can be avoided, and toxicity problems are eliminated.Bromine may be used instead of iodine, but chlorine proves unsatisfactory as an oxidant.