66735-14-6

Basic information

• Product Name: 2-Propenoic acid, 3-(4-bromophenyl)-2-methyl-
• CAS NO: 66735-14-6
• Molecular Formula: C10H9BrO2
• Molecular Weight: 241.084
• Mol File: 66735-14-6.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 2-Propenoic acid, 3-(4-bromophenyl)-2-methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Propenoic acid, 3-(4-bromophenyl)-2-methyl-(66735-14-6)
• EPA Substance Registry System: 2-Propenoic acid, 3-(4-bromophenyl)-2-methyl-(66735-14-6)

Safety Data

• Hazardous Substances Data: 66735-14-6(Hazardous Substances Data)

Upstream product

• 123-62-6 propionic acid anhydride 
• 1122-91-4 4-bromo-benzaldehyde 
• 106-40-1 4-bromo-aniline 
• 251320-24-8 2-[(4-bromo-phenyl)-hydroxy-methyl]-acrylic acid methyl ester 
• 1367876-28-5 [(Z)-3-(4-bromophenyl)-2-methoxycarbonyl-2-propenyl]triphenylphosphonium bromide 
• 103519-90-0 3-(4-bromophenyl)-2-methylacrylic acid ethyl ester 
• 137-40-6 sodium proprionate 
• 110-89-4 piperidine 
• 516-05-2 methyl-propanedioic acid 

Downstream Products

• 66735-01-1 3-(4-bromophenyl)-2-methylpropanoic acid 
• 1285505-93-2 N-[(E)-3-(4-bromo-phenyl)-2-methyl-acryloyl]-guanidine 
• 1285505-56-7 N-[(E)-3-(4-furan-3-yl-phenyl)-2-methyl-acryloyl]-guanidine 
• 1040274-42-7 (S)-3-(4-Bromophenyl)-2-methylpropionic acid 
• 23773-30-0 (4-bromophenyl)-1-propyne 
• 90766-74-8 4-Brom-β-brom-α-methyl-zimtsaeure 

Relevant articles and documents

Catalytic, enantioselective 1,2-difluorination of cinnamamides

The enantio- and diastereoselective synthesis of 1,2-difluorides via chiral aryl iodide-catalyzed difluorination of cinnamamides is reported. The method uses HF-pyridine as a fluoride source and mCPBA as a stoichiometric oxidant to turn over catalyst, and

Copper-Photocatalyzed Contra-Thermodynamic Isomerization of Polarized Alkenes

The contra-thermodynamic isomerization of α- and β-substituted cinnamate derivatives catalyzed by the Cu(OAc)2/rac-BINAP complex under blue light irradiation is reported. The use of an oxazolidinone template, which favored the complexation of the copper catalyst to the substrate, allowed the E → Z isomerization of the catalytically formed chromophore under simple and robust reaction conditions in good to excellent ratios. The mechanism of this process based on the transient formation of a chromophore was also studied.

Microwave-assisted synthesis of the (E)-α-methylalkenoate framework from multifunctionalized allylic phosphonium salts

A convenient and general microwave-assisted method for the synthesis of stereochemically defined α-methylalkenoic acids and esters from allylic phosphonium salts in a basic aqueous medium is described. A selective preparation of acids or esters was dependent on the base (NaOH or NaHCO 3) employed in the reaction and could be achieved with good to excellent yields under mild conditions in the absence of hydrides and reducing agents.