6674-45-9 Usage
Description
[[[(2R,3S,4R,5R)-5-(2-amino-6-oxo-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl] [(2R,3S,4R,5R)-5-(2-amino-6-oxo-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl hydrogen phosphate is a complex nucleotide molecule that consists of a purine base (2-amino-6-oxo-3H-purin-9-yl) attached to a dihydroxyoxolan-2-yl group and combined with hydroxyphosphoryl and methoxy-hydroxyphosphoryl groups. It also contains a hydrogen phosphate group. [[[(2R,3S,4R,5R)-5-(2-amino-6-oxo-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl] [(2R,3S,4R,5R)-5-(2-amino-6-oxo-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl hydrogen phosphate serves as a building block of DNA and RNA and plays a crucial role in various cellular functions, including energy transfer, cell signaling, and enzyme reactions. Its complex structure and involvement in genetic information transfer and storage make it significant in biochemistry and cellular biology.
Uses
Used in Biochemical Research:
[[[(2R,3S,4R,5R)-5-(2-amino-6-oxo-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl] [(2R,3S,4R,5R)-5-(2-amino-6-oxo-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl hydrogen phosphate is used as a research tool for studying the structure and function of nucleotides in DNA and RNA, as well as their role in cellular processes.
Used in Pharmaceutical Development:
This complex nucleotide is used as a starting material or intermediate in the development of new drugs targeting various cellular functions and diseases, particularly those related to genetic information transfer and storage.
Used in Diagnostic Applications:
In the medical industry, this compound can be used for the development of diagnostic tools and tests that detect or monitor specific cellular functions or conditions related to nucleotide metabolism and genetic information processing.
Used in Genetic Engineering:
In the field of genetic engineering, [[[(2R,3S,4R,5R)-5-(2-amino-6-oxo-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl] [(2R,3S,4R,5R)-5-(2-amino-6-oxo-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl hydrogen phosphate can be employed as a component in the design and synthesis of novel genetic constructs or for the manipulation of genetic information in various organisms.
Check Digit Verification of cas no
The CAS Registry Mumber 6674-45-9 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,6,7 and 4 respectively; the second part has 2 digits, 4 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 6674-45:
(6*6)+(5*6)+(4*7)+(3*4)+(2*4)+(1*5)=119
119 % 10 = 9
So 6674-45-9 is a valid CAS Registry Number.
InChI:InChI=1/2C10H13N5O5.3H3O4P/c2*11-10-13-7-4(8(19)14-10)12-2-15(7)9-6(18)5(17)3(1-16)20-9;3*1-5(2,3)4/h2*2-3,5-6,9,16-18H,1H2,(H3,11,13,14,19);3*(H3,1,2,3,4)/t2*3-,5-,6-,9-;;;/m11.../s1
6674-45-9Relevant articles and documents
One-Pot Synthesis of α,γ-Dinucleoside 5'-Triphosphates, G5'pppG and A5'pppA, Using S,S'-Bis(4-chlorophenyl)phosphorodithioate
Fukuoka, Koichiro,Suda, Fuminori,Suzuki, Ryo,Ishikawa, Masahide,Hata, Tsujiaki
, p. 499 - 502 (2007/10/02)
S,S'-Bis(4-chlorophenyl) phosphorodithioate was useful for the synthesis of α,γ-dinucleoside 5'-triphosphates, G5'pppG and A5'pppA starting from the corresponding unprotected nucleoside 5'-phosphates under neutral conditions. G5'pppG was used for the synthesis of m7G5'pppG by means of the N7-methylation of one of two guanine moieties of G5'pppG.