667466-76-4

Basic information

• Product Name: 4-benzyl-6-(phenoxathiin-2-yl)-3-(N-phthalyl-L-valyl)oxy-pyrimidine
• Synonyms: 4-benzyl-6-(phenoxathiin-2-yl)-3-(N-phthalyl-L-valyl)oxy-pyrimidine
• CAS NO: 667466-76-4
• Molecular Weight: 613.693
• Mol File: 667466-76-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 4-benzyl-6-(phenoxathiin-2-yl)-3-(N-phthalyl-L-valyl)oxy-pyrimidine(CAS DataBase Reference)
• NIST Chemistry Reference: 4-benzyl-6-(phenoxathiin-2-yl)-3-(N-phthalyl-L-valyl)oxy-pyrimidine(667466-76-4)
• EPA Substance Registry System: 4-benzyl-6-(phenoxathiin-2-yl)-3-(N-phthalyl-L-valyl)oxy-pyrimidine(667466-76-4)

Safety Data

• Hazardous Substances Data: 667466-76-4(Hazardous Substances Data)

Upstream product

• 667466-68-4 6-(phenoxathiin-2-yl)-2,3,4,5-tetrahydropyridazin-3-one 
• 59502-37-3 4-(phenoxathiin-2-yl)-4-oxobutanoic acid 
• 6306-54-3 N-phthaloyl L-valine 
• 667466-69-5 4-benzyl-6-(phenoxathiin-2-yl)pyridazin-3(2H)-one 

Relevant articles and documents

γ-oxo carboxylic acids in heterocyclic synthesis: Part IV - Synthesis of some pyridazines containing phthalyl and tosyl amino acids using DCC as the condensing agent

3(2H)-Oxo-, 3-mercapto- or 3-amino-pyridazine derivatives 3,5 and 6 have been coupled with N-phthalyl- or N-tosyl-amino acids in one-step at room temperature by using N,N′-dicyclohexylcarbodiimide as the condensing agent to furnish the corresponding 3-N-(phthalyl- or tosyl-amino acids) pyridazine derivatives (7-9)a-h, respectively. Hydrazinolysis of the N-phthalyl derivatives (7-9)a-d in methanol yields the corresponding unprotected derivatives (7-9)M 9)i-l. The anti-bacterial activity of the prepared compounds has been tested.