66761-27-1

Basic information

• Product Name: 4-azidosalicylic acid
• Synonyms: 4-Azido-2-hydroxybenzoic Acid;4-Azido-2-hydroxy-benzoic Acid
• CAS NO: 66761-27-1
• Molecular Formula: C₇H₅N₃O₃
• Molecular Weight: 179.1329
• Product Categories: Aromatics;Photoaffinity Labels
• Mol File: 66761-27-1.mol
• Article Data: 14

Chemical Properties

• Melting Point: 190-193°C (dec.)
• Appearance: /
• Storage Temp.: Amber Vial, -20°C Freezer
• CAS DataBase Reference: 4-azidosalicylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 4-azidosalicylic acid(66761-27-1)
• EPA Substance Registry System: 4-azidosalicylic acid(66761-27-1)

Safety Data

• RIDADR: 1325
• HazardClass: 4.1
• PackingGroup: III
• Hazardous Substances Data: 66761-27-1(Hazardous Substances Data)

Usage

Description

4-Azidosalicylic acid is an aryl azide compound characterized by its light brown solid appearance. It possesses unique chemical properties that make it suitable for various applications, particularly in the field of photofunctionalization.

Uses

Used in Photofunctionalization Applications:
4-Azidosalicylic acid is used as a photoactive compound for photofunctionalization processes. Its aryl azide nature allows it to undergo specific chemical reactions upon exposure to light, making it a valuable tool in various research and industrial applications.
Used in Chemical Synthesis:
4-Azidosalicylic acid is used as a synthetic building block in the chemical industry. Its unique structure and reactivity enable the creation of a wide range of compounds with diverse properties and potential applications.
Used in Research and Development:
In the field of research and development, 4-Azidosalicylic acid is employed as a key component in the study of photochemical reactions and the development of new materials and processes that rely on light-induced transformations.
Used in Pharmaceutical Industry:
4-Azidosalicylic acid may also find applications in the pharmaceutical industry, where its photofunctionalization properties could be harnessed for the development of light-activated drugs or drug delivery systems with enhanced targeting and release profiles.
Used in Material Science:
In material science, 4-Azidosalicylic acid can be utilized in the development of novel materials with light-responsive properties, such as smart coatings, sensors, or optical devices that change their characteristics upon exposure to light.

InChI:InChI=1/C7H5N3O3/c8-10-9-5-1-4(7(12)13)2-6(11)3-5/h1-3,11H,(H,12,13)

Upstream product

• 65-49-6 4-Aminosalicylic acid 
• 133-10-8 sodium p-aminosalicylate 
• 50-00-0 formaldehyd 
• 51642-25-2 3-azidophenol 

Downstream Products

• 87877-90-5 methyl 4-azido-2-hydroxybenzoate 
• 86979-61-5 6-(4-azido-2-hydroxybenzamido)-6-deoxy-1,2:3,4-di-O-isopropylidene-α-D-galactopyranose 
• 96602-46-9 succinimide 4-azidosalicylate 
• 86979-59-1 4-azidosalicoyl chloride 
• 152564-60-8 tert-butyldimethylsilyl 4-azido-2-<(tert-butyldimethylsilyl)oxy>benzoate 
• 929038-60-8 4-azido-2-hydroxy-benzoic acid 4,4,7a-trimethyl-octahydro-inden-1-yl ester 
• 929038-62-0 2-(3-amino-propoxy)-4-azido-benzoic acid 4,4,7a-trimethyl-octahydro-inden-1-yl ester 
• 929038-61-9 4-azido-2-(3-tert-butoxycarbonylamino-propoxy)-benzoic acid 4,4,7a-trimethyl-octahydro-inden-1-yl ester 
• 874163-10-7 3(R)-[(4(R)-((4-azido-2-hydroxybenzoyl)amino)-1-(tert-butoxycarbonyl)-2(S)-pyrrolidinylcarbonyl)amino]-2-oxo-1-pyrrolidineacetamide 
• 874163-07-2 3(R)-[(4(S)-((4-azido-2-hydroxybenzoyl)amino)-1-(tert-butoxycarbonyl)-2(S)-pyrrolidinylcarbonyl)amino]-2-oxo-1-pyrrolidineacetamide 
• 874163-21-0 3(R)-[(2(S)-1-(tert-butoxycarbonyl)pyrrolidinylcarbonyl)amino]-2-oxo-1-pyrrolidineacetamide N-(N'-(4-azido-2-hydroxybenzoyl)amino)ethyl 
• 874163-11-8 3(R)-[(4(R)-((4-azido-2-hydroxy-5-iodobenzoyl)amino)-1-(tert-butoxycarbonyl)-2(S)-pyrrolidinylcarbonyl)amino]-2-oxo-1-pyrrolidineacetamide 
• 874163-08-3 3(R)-[(4(S)-((4-azido-2-hydroxy-5-iodobenzoyl)amino)-1-(tert-butoxycarbonyl)-2(S)-pyrrolidinylcarbonyl)amino]-2-oxo-1-pyrrolidineacetamide 
• 874163-22-1 3(R)-[(2(S)-1-(tert-butoxycarbonyl)pyrrolidinylcarbonyl)amino]-2-oxo-1-pyrrolidineacetamide N-(N'-(4-azido-2-hydroxy-5-iodobenzoyl)amino)ethyl 

Relevant articles and documents

Synthesis, characterization and cytotoxic activity evaluation of 4-(1,2,3-triazol-1-yl) salicylic acid derivatives

A novel series of 4-(1,2,3-triazol-1-yl) salicylic acid derivatives was synthesized from 4-azidosalicylic acid and diverse alkynes using copper catalyzed azide-alkyne cycloaddition as key process and fully characterized by using different analytical techn

Controlled Supramolecular Assembly Inside Living Cells by Sequential Multistaged Chemical Reactions

Synthetic assembly within living cells represents an innovative way to explore purely chemical tools that can direct and control cellular behavior. We use a simple and modular platform that is broadly accessible and yet incorporates highly intricate molecular recognition, immolative, and rearrangement chemistry. Short bimodular peptide sequences undergo a programmed sequence of events that can be tailored within the living intracellular environment. Each sequential stage of the pathways beginning with the cellular uptake, intracellular transport, and localization imposes distinct structural changes that result in the assembly of fibrillar architectures inside cells. The observation of apoptosis, which is characterized by the binding of Annexin V, demonstrates that programmed cell death can be promoted by the peptide assembly. Higher complexity of the assemblies was also achieved by coassembly of two different sequences, resulting in intrinsically fluorescent architectures. As such, we demonstrate that the in situ construction of architectures within cells will broaden the community's perspective toward how structure formation can impact a living system.

LANTHANIDE CLUSTERS AND METHODS OF USE THEREOF

The present invention is directed to multinuclear lanthanides chiral clusters, based on phenyl-oxazoline-amide (POxA) ligands, and to methods of use thereof. The chiral clusters of this invention are highly fluorescent with high stability.