668273-74-3 Usage
Description
Linagliptin Impurity S, also known as (S)-Linagliptin tert-Butyl Ester, is an intermediate in the synthesis of a novel potent and selective dipeptidyl peptidase-4 (DPP-4) inhibitor. It plays a crucial role in the development of pharmaceuticals for the treatment of type 2 diabetes.
Used in Pharmaceutical Industry:
Linagliptin Impurity S is used as an intermediate in the synthesis of DPP-4 inhibitors for the treatment of type 2 diabetes. Its selective and potent nature makes it a valuable component in the development of effective medications to manage blood sugar levels in diabetic patients.
Check Digit Verification of cas no
The CAS Registry Mumber 668273-74-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,6,8,2,7 and 3 respectively; the second part has 2 digits, 7 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 668273-74:
(8*6)+(7*6)+(6*8)+(5*2)+(4*7)+(3*3)+(2*7)+(1*4)=203
203 % 10 = 3
So 668273-74-3 is a valid CAS Registry Number.
668273-74-3Relevant articles and documents
METHOD FOR PREPARING AN IMPORTANT INTERMEDIATE OF LINAGLIPTIN
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, (2015/12/20)
The present invention discloses an improved process for preparing an important intermediate of linagliptin. In particular, disclosed are a process for preparing a compound V which is an important intermediate of linagliptin and has the structure V, and an industrial process of preparing linagliptin having excellent chemical and optical purities, which is an inhibitor of dipeptidyl peptidase-4 (DPP-IV), from the compound V. The process employs a phase-transfer catalyst, is high in yield, easy and simple to handle, environmentally friendly, suitable for industrial mass production, and can be implemented by a “one-pot process”.
