669068-63-7

Basic information

• Product Name: 4-Piperidinecarbonitrile, 4-(3,4-difluorophenyl)-1-methyl-
• CAS NO: 669068-63-7
• Molecular Formula: C13H14F2N2
• Molecular Weight: 236.264
• Mol File: 669068-63-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 4-Piperidinecarbonitrile, 4-(3,4-difluorophenyl)-1-methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Piperidinecarbonitrile, 4-(3,4-difluorophenyl)-1-methyl-(669068-63-7)
• EPA Substance Registry System: 4-Piperidinecarbonitrile, 4-(3,4-difluorophenyl)-1-methyl-(669068-63-7)

Safety Data

• Hazardous Substances Data: 669068-63-7(Hazardous Substances Data)

Upstream product

• 658-99-1 (3,4-difluorophenyl)acetonitrile 
• 55-86-7 mechlorethamine hydrochloride 

Downstream Products

• 906369-62-8 4-(3,4-difluoro-phenyl)-4-(methanesulfonylamino-methyl)-piperidine-1-carboxylic acid tert-butyl ester 
• 906369-56-0 4-cyano-4-(3,4-difluoro-phenyl)-piperidine-1-carboxylic acid tert-butyl ester 

Relevant articles and documents

Preparation of 2,3-dihydro-1H-spiro[isoquinoline-4,4′-piperidine] via an N-sulfonyl Pictet-Spengler reaction

A high yielding synthesis of variously substituted 2,3-dihydro-1H-spiro[isoquinoline-4,4′-piperidine] is reported. N-(2-nitrophenyl)sulfonyl was successfully used as both an activating and protecting group for the key Pictet-Spengler reaction.