6700-17-0 Usage
Description
Sodium Propionate, also known as sodium propanoate, is a chemical compound with the formula C3H5NaO2. It is a white crystalline solid that is soluble in water and has a slightly salty taste. Sodium propionate is a salt derived from propionic acid and is commonly used as a food preservative due to its ability to inhibit the growth of mold, yeast, and some bacteria.
Uses
Used in Food Industry:
Sodium Propionate is used as a food preservative for its antifungal ability towards grain products. It helps to extend the shelf life of bread, cakes, and other baked goods by preventing mold growth and spoilage. Additionally, it is used in the preservation of meat, fish, and dairy products to maintain freshness and prevent spoilage.
Used in Animal Feed Industry:
Sodium Propionate is also used as a preservative in animal feed to prevent the growth of mold and bacteria, ensuring the feed remains fresh and safe for consumption by animals.
Used in Cosmetics Industry:
In the cosmetics industry, Sodium Propionate is used as a preservative in various products such as creams, lotions, and shampoos to prevent microbial contamination and extend the shelf life of the products.
Used in Pharmaceutical Industry:
Sodium Propionate is utilized as a preservative in pharmaceutical formulations to maintain the stability and safety of the products by inhibiting the growth of microorganisms.
Production Methods
Sodium propionate is prepared by the reaction of propionic acid
with sodium carbonate or sodium hydroxide.
Pharmaceutical Applications
As an excipient, sodium propionate is used in oral pharmaceutical
formulations as an antimicrobial preservative. Like propionic acid,
sodium propionate and other propionic acid salts are fungistatic
and bacteriostatic against a number of Gram-positive cocci.
Propionates are more active against molds than is sodium benzoate,
but have essentially no activity against yeasts.
Therapeutically, sodium propionate has been used topically in
concentrations up to 10% w/w alone or in combination with other propionates, caprylates, or other antifungal agents, in the form of
ointments or solutions for the treatment of dermatophyte infections.
Eye drops containing 5% w/v sodium propionate have also been
used.
In food processes, particularly baking, sodium propionate is
used as an antifungal agent; it may also be used as a flavoring agent
in food products. In veterinary medicine, sodium propionate is used
therapeutically as a glucogenic substance in ruminants.
Safety
Sodium propionate and other propionates are used in oral
pharmaceutical formulations, food products, and cosmetics. The
free acid, propionic acid, occurs naturally at levels up to 1% w/w in
certain cheeses.
Following oral consumption, propionate is metabolized in
mammals in a manner similar to that of fatty acids. Toxicity studies
in animals have shown sodium propionate and other propionates to
be relatively nontoxic materials.(2,3) In veterinary medicine, sodium
propionate is used as a therapeutic agent for cattle and sheep.
In humans, 6 g of sodium propionate has been administered
daily without harm.(2) However, allergic reactions to propionates
can occur.
LD50 (mouse, oral): 6.33 g/kg
LD50 (mouse, SC): 2.1 g/kg
LD50 (rabbit, skin): 1.64 g/kg
storage
Sodium propionate is deliquescent and should therefore be stored in
an airtight container in a cool, dry place.
Incompatibilities
Incompatibilities for sodium propionate are similar to those of other
weak organic acids.
Regulatory Status
GRAS listed. Accepted for use as a food additive in Europe. In
cheese products, propionates are limited to 0.3% w/w concentration;
a limit of 0.32% w/w is applied in flour and white bread rolls,
while a limit of 0.38% w/w is applied in whole wheat products.
Included in the FDA Inactive Ingredients Database (oral
capsules, powder, suspensions, and syrups). Included in nonparenteral
medicines licensed in the UK. Included in the Canadian List
of Acceptable Non-medicinal Ingredients.
Check Digit Verification of cas no
The CAS Registry Mumber 6700-17-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,7,0 and 0 respectively; the second part has 2 digits, 1 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 6700-17:
(6*6)+(5*7)+(4*0)+(3*0)+(2*1)+(1*7)=80
80 % 10 = 0
So 6700-17-0 is a valid CAS Registry Number.
InChI:InChI=1/C3H6O2.Na.H2O/c1-2-3(4)5;;/h2H2,1H3,(H,4,5);;1H2/q;+1;/p-1
