6700-34-1 Usage
Description
Dextromethorphan hydrobromide monohydrate is a dextrorotatory morphinan derivative with structural similarities to levorphanol, codeine, and morphine. It is a potent antitussive agent that does not exhibit opioid activity, making it a safe alternative for cough suppression. Dextromethorphan hydrobromide monohydrate is known for its ability to bind and inhibit NMDA and nicotinic receptors, as well as block receptor-gated and voltage-gated calcium and sodium channels, contributing to its multimodal analgesic properties for acute and neuropathic pain management.
Uses
Used in Pharmaceutical Industry:
Dextromethorphan hydrobromide monohydrate is used as an antitussive drug for the treatment of cough due to its strong cough suppressant effects without inducing opioid activity. It is an orally active synthetic morphine analog that provides relief from coughing without the risk of addiction or dependence associated with traditional opioids.
Used in Pain Management:
Dextromethorphan hydrobromide monohydrate is used as an analgesic in multimodal pain therapies, particularly for acute and neuropathic pain. Its ability to inhibit NMDA and nicotinic receptors, as well as block various ion channels, makes it a valuable component in comprehensive pain management strategies.
Used as an Opioid Ligand:
In research and development, dextromethorphan hydrobromide monohydrate serves as an opioid ligand, aiding in the study and development of new medications targeting the opioid receptors. This application helps in understanding the mechanisms of action and potential therapeutic benefits of opioid-related compounds, while also exploring ways to mitigate their addictive properties.
Biological Activity
Non-competitive, low affinity NMDA receptor antagonist. Antitussive, anticonvulsive and neuroprotective agent.
Check Digit Verification of cas no
The CAS Registry Mumber 6700-34-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,7,0 and 0 respectively; the second part has 2 digits, 3 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 6700-34:
(6*6)+(5*7)+(4*0)+(3*0)+(2*3)+(1*4)=81
81 % 10 = 1
So 6700-34-1 is a valid CAS Registry Number.
InChI:InChI=1/C18H25NO.BrH.H2O/c1-19-10-9-18-8-4-3-5-15(18)17(19)11-13-6-7-14(20-2)12-16(13)18;;/h6-7,12,15,17H,3-5,8-11H2,1-2H3;1H;1H2/t15-,17-,18-;;/m1../s1
6700-34-1Relevant articles and documents
Controlled release powder and process for its preparation
-
, (2008/06/13)
A controlled release powder containing discrete micro-particles for use in edible, pharmaceutical and other controlled release compositions is disclosed. The micro-particles have an average size in the range of from 0.1 to 125 μm. Each of the micro-particles is in the form of a micromatrix of an active ingredient uniformly distributed in at least one non-toxic polymer. The micro-particles have a predetermined release of active ingredient when the dissolution rate thereof is measured according to the Paddle Method of U.S. Pharmacopoeia XX at 37° C. and 75 r.p.m.
This product is a nationally controlled contraband, and the Lookchem platform doesn't provide relevant sales information.