67089-07-0Relevant articles and documents
Kinetically controlled diastereoselective synthesis of CPS124, a carnitine monothiophosphate
Prasad, Kapa,Xu, David D.,Tempkin, Orin,Villhauer, Edwin B.,Repic, Oljan
, p. 743 - 749 (2003)
An expedient synthesis of CPS124 (1) is described using the diastereoselective reaction of the in situ generated dichlorophosphite 6 with L-carnitine tetrafluoroborate salt 7 under kinetic control as the key step. Alkylations of resorcinol 2 and its benzoate 13 are discussed. The use of α-cellulose as a support for solids that are difficult to filter or low melting is presented.
AMINE COMPOUNDS HAVING ANTI-INFLAMMATORY, ANTIFUNGAL, ANTIPARASITIC AND ANTICANCER ACTIVITY
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Page/Page column 94, (2014/08/19)
Amine compounds having activity against inflammation, fungi, unicellular parasitic microorganisms, and cancer are described. The compounds contain a monocyclic, bicyclic, or tricyclic aromatic ring having one, two, or three ring nitrogen atoms.
DERIVATIVES OF 4-TRIMETHYLAMMONIUM-3-AMINOBUTYRATE AND 4-TRIMETHYLPHOSPHONIUM-3-AMINOBUTYRATE AS CPT-INHIBITORS
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Page/Page column 15-18, (2008/06/13)
The invention provides a new class of compounds capable of inhibiting carnitine palmitoyl transferase (CPT) having formula (I). The invention also relates to pharmaceutical compositions, which comprise at least one new compound according to the invention,
