67111-66-4

Basic information

• Product Name: (1R)-(+)-CAMPHANIC ACID
• Synonyms: (+)-CAMPHANIC ACID;(1R)-(+)-CAMPHANIC ACID;(1R)-3-OXO-4,7,7-TRIMETHYL-2-OXABICYCLO[2.2.1]HEPTANE-1-CARBOXYLIC ACID;2-Oxabicyclo2.2.1heptane-1-carboxylic acid, 4,7,7-trimethyl-3-oxo-, (1R,4S)-;D-(1S,3R)-(-)-CAMPHORIC ACID;(1R)-4,7,7-Trimethyl-3-oxo-2-oxabicyclo[2.2.1]heptane-1-carboxylic acid, (1R)-3-Oxo-4,7,7-trimethyl-2-oxabicyclo[2.2.1]heptane-1-carboxylic acid;(1R)-4,7,7-Trimethyl-3-oxo-2-oxabicyclo[2.2.1]heptane-1-carboxylic acid;(1S,4R)-1,7,7-trimethyl-2-oxo-3-oxabicyclo[2.2.1]heptane-4-carboxylic acid
• CAS NO: 67111-66-4
• Molecular Formula: C₁₀H₁₄O₄
• Molecular Weight: 198.22
• Product Categories: Chiral Compound
• Mol File: 67111-66-4.mol
• Article Data: 7

Chemical Properties

• Melting Point: 200-202 °C(lit.)
• Boiling Point: 355.5 °C at 760 mmHg
• Flash Point: 142.1 °C
• Appearance: /
• Density: 1.296 g/cm³
• Vapor Pressure: 5.19E-06mmHg at 25°C
• Refractive Index: 1.532
• Storage Temp.: 2-8°C
• PKA: 3.36±0.60(Predicted)
• CAS DataBase Reference: (1R)-(+)-CAMPHANIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: (1R)-(+)-CAMPHANIC ACID(67111-66-4)
• EPA Substance Registry System: (1R)-(+)-CAMPHANIC ACID(67111-66-4)

Safety Data

• Hazard Codes: Xn
• Statements: 20/21/22-36/37/38
• Safety Statements: 22-24/25-36-26
• WGK Germany: 3
• Hazardous Substances Data: 67111-66-4(Hazardous Substances Data)

Usage

Uses

Chiral auxiliary in the synthesis of azasugars.

InChI:InChI=1/C10H14O4/c1-8(2)9(3)4-5-10(8,6(11)12)14-7(9)13/h4-5H2,1-3H3,(H,11,12)/t9-,10+/m1/s1

Upstream product

• 10333-96-7 1-Bromo-5,8,8-trimethyl-3-oxa-bicyclo[3.2.1]octane-2,4-dione 
• 88764-13-0 (1R,2R,4R)-2-exo-cyano-7-oxabicyclo<2.2.1>hept-5-en-2-endo-yl(1S)-camphanate 
• 87859-84-5 (-)-(1R,3R)-3-chlorocamphoric anhydride 
• 39637-74-6 (1S)-(-)-camphanic chloride 
• 88701-62-6 1-(Cyanovinyl) (1'S)-camphanate 
• 124-83-4 D-(+)-camphoric acid 
• 87859-83-4 α-chlorocamphoric acid dichloride 
• 48138-74-5 1,2,2-trimethyl-cyclopentane-1,3-dicarbonyl chloride 
• 124-83-4 (+)-camphoric acid 
• 432036-81-2 (-)-(1S,4R)-camphanic acid [(5-benzyloxy-2-hydroxy-1,2,3,4-tetrahydronaphth-2-yl)methyl]ester 
• 432036-82-3 (-)-(1S,4R)-camphanic acid [((2R)-5-benzyloxy-2-hydroxy-1,2,3,4-tetrahydronaphth-2-yl)methyl]ester 

Downstream Products

• 138403-92-6 (R)-Methoxy-phenyl-acetic acid (4bR,8aR,9R)-7-[1-ethoxycarbonyl-meth-(E)-ylidene]-2-methoxy-4b,5,6,7,8,8a,9,10-octahydro-phenanthren-9-yl ester 
• 133098-41-6 4'-N-camphanyl-(4'R)-<4-2H1>-3,5'-O-dibenzylpyridoxamine 
• 133008-70-5 4'-N-camphanyl-(4'S)-<4-2H1>-3,5'-O-dibenzylpyridoxamine 
• 133008-61-4 (4'R)-<4'-2H1>-3,5'-O-dibenzylpyridox-4'-yl camphanate 
• 133098-40-5 (4'S)-<4'-2H1>-3,5'-O-dibenzylpyridox-4'-yl camphanate 
• 142696-11-5 (1S,4R)-4,7,7-Trimethyl-3-oxo-2-oxa-bicyclo[2.2.1]heptane-1-carboxylic acid 1-[(R)-2-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-3-phenyl-propionyl]-1H-pyrrol-2-ylmethyl ester 
• 142597-20-4 (1S,4R)-4,7,7-Trimethyl-3-oxo-2-oxa-bicyclo[2.2.1]heptane-1-carboxylic acid 1-[(S)-2-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-3-phenyl-propionyl]-1H-pyrrol-2-ylmethyl ester 
• 39637-74-6 (-)-ω-camphanic acid chloride 
• 84064-04-0 (-)-methyl 4-<3-<3-<2-<1-<(1S)-ω-camphanyloxy>cyclohexyl>ethyl>-4-oxo-2-thiazolidinyl>propyl>benzoate 
• 84040-69-7 (+)-methyl 4-<3-<3-<2-<1-<(1S)-ω-camphanyloxy>cyclohexyl>ethyl>-4-oxo-2-thiazolidinyl>propyl>benzoate 
• 39637-74-6 (1S)-(-)-camphanic chloride 
• 245655-52-1 (1R)-3,4-dehydrocamphoroyl difluoride 
• 245655-48-5 (1R,4S)-camphanoyl fluoride 
• 245655-46-3 (1R,4S)-(-)-3-oxa-4-trifluoromethylcamphor 

Relevant articles and documents

Practical synthesis of PGI2 agonist: Resolution-inversion- recycle approach of its chiral intermediate

Practical synthesis of ((2R)-5-benzyloxy-2-hydroxy-1,2,3,4- tetrahydronaphth-2-yl)methanol ((R)-7b), a key chiral intermediate for the synthesis of the novel PGI2 agonist, (R)-[6-[(diphenylcarbamoyloxy) methyl]-6-hydroxy-5,6,7,8-tetrahydronapht

(-)-(1S,4R)-camphanoyl chloride

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182. The Preparation of Optically Pure 7-Oxabicyclohept-2-ene Derivatives. The CD Spectrum of (+)-(1R)-7-Oxabicyclohept-5-en-2-one

(-)-1-Camphanoyloxyacrylonitrile (=(-)-1-cyanovinyl camphanate; 1) obtained from the commercially available (-)-camphanoyl chloride and 2-oxopropiononitrile added to furan at 20 deg C in the presence of Cu(BF4)2*6H2O or ZnI2 and gave a mixture of 2-cyano-