67231-69-0Relevant articles and documents
Synthesis of new bis-iminocoumarins by Schmidt reaction catalyzed by ion-exchange resins
Ammar, Houcine,Fakhfakh, Mehdi,Le Bigot, Yves,El Gharbi, Rachid
, p. 1821 - 1828 (2003)
A new synthetic route to bis-iminocoumarins is proposed which involves the synthesis of iminocoumarins from reaction of 2-hydroxybenzaldehydes with arylacetonitriles and their coupling with aromatic diamines. Ion-exchange resins were used as catalysts in
Iminocoumarin based fluorophores: Indispensable scaffolds for rapid, selective and sensitive detection of thiophenol
Kand, Dnyaneshwar,Mandal, Prashant Sahebrao,Datar, Avdhoot,Talukdar, Pinaki
, p. 25 - 31 (2014/04/03)
Off-on fluorescence probes for the detection of thiophenol were designed based on the reaction mechanism to ensure rapid sensing process. 2,4-Dinitrophenylsulfonyl based probes with iminocoumarin fluorophores were validated by theoretical calculations for their off-fluorescence states. Reaction of these probes with thiophenol released strong fluorescent iminocoumarin species with good response times. These results, upon comparing with reported probes, confirmed that higher pKaH values of the imino nitrogen of iminocoumarins are important for rapid sensing process. Reactivity of these probes was limited to only thiophenol and no reaction was observed with aliphatic thiols. The benzothiazole substituted probe displayed up to 260-fold fluorescence enhancement upon reaction with thiophenol. Sensing of the analyte by the probe was characterized by change in color from red to yellow and with appearance of the green fluorescence. A detection limit up to 6.9 × 10-9 M was also determined for this probe.
Polymer supported reagents: Novel methodology for selective and general synthesis of iminocoumarins
Mhiri,El Gharbi,Le Bigot
, p. 3385 - 3399 (2007/10/03)
A selective synthesis of iminocoumarins 3 was accomplished, starting from salicylaldehydes 1 and nitriles 2, by the use of Amberlite IRA 900 resin as a polymeric solid support. The possibility of using various arylacetonitriles enhances the synthetic vers