67237-52-9

Basic information

• Product Name: 2-ETHYNYL-1-METHYL-1H-PYRROLE
• Synonyms: 2-ETHYNYL-1-METHYL-1H-PYRROLE
• CAS NO: 67237-52-9
• Molecular Formula: C₇H₇N
• Molecular Weight: 105.13718
• Mol File: 67237-52-9.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-ETHYNYL-1-METHYL-1H-PYRROLE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-ETHYNYL-1-METHYL-1H-PYRROLE(67237-52-9)
• EPA Substance Registry System: 2-ETHYNYL-1-METHYL-1H-PYRROLE(67237-52-9)

Safety Data

• Hazardous Substances Data: 67237-52-9(Hazardous Substances Data)

Upstream product

• 31785-72-5 1-methyl-2-pyrrolyllithium 
• 2713-09-9 fluoroethyne 
• 868835-14-7 1-methyl-2-trimethylsilanylethynyl-1H-pyrrole 
• 34671-29-9 2-iodo-1-methyl-1H-pyrrole 
• 4301-14-8 acetylenemagnesium bromide 
• 96-54-8 N-Methylpyrrole 

Downstream Products

• 144912-17-4 1-methyl-2-(2-phenylethynyl)-1H-pyrrole 

Relevant articles and documents

Direct synthesis of heteroarylethynes via palladiumcatalyzed coupling of heteroaryl halides with ethynylzinc halides. Its application to an efficient synthesis of a thiophenelactone from chamaemelum nobile

A variety of terminal alkynes containing a heteroaryl group can be directly and selectively synthesized by the Pd-catalyzed coupling of heteroaryl iodides or bromides with ethynylzinc halides. Various compounds of this class containing furan, thiophene, and pyridine have been prepared, and the procedure has been applied to an efficient and selective synthesis of a thiophenelactone from Chamaemelum nobile L.

Unusually sluggish copper(I)catalyzed oxidative dimerization of 2-ethynyl-1-methylpyrrole

Reaction of 2-ethynyl-1-methylpyrrole with oxygen in the presence of catalytic amounts of copper(I)chloride proceeds only upon addition of 1,8-diazabicycloundec-7-ene (DBU).