67287-60-9

Basic information

• Product Name: Benzenemethanol, a-[[[2-(2-chloro-3,4-dimethoxyphenyl)ethyl]amino]methyl]-3-methoxy-
• CAS NO: 67287-60-9
• Molecular Formula: C19H24ClNO4
• Molecular Weight: 365.857
• Mol File: 67287-60-9.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: Benzenemethanol, a-[[[2-(2-chloro-3,4-dimethoxyphenyl)ethyl]amino]methyl]-3-methoxy-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenemethanol, a-[[[2-(2-chloro-3,4-dimethoxyphenyl)ethyl]amino]methyl]-3-methoxy-(67287-60-9)
• EPA Substance Registry System: Benzenemethanol, a-[[[2-(2-chloro-3,4-dimethoxyphenyl)ethyl]amino]methyl]-3-methoxy-(67287-60-9)

Safety Data

• Hazardous Substances Data: 67287-60-9(Hazardous Substances Data)

Upstream product

• 67287-36-9 2-(2-chloro-3,4-dimethoxyphenyl)ethylamine 
• 2181-42-2 trimethylsulphonium iodide 
• 591-31-1 3-methoxy-benzaldehyde 
• 32017-77-9 2-(m-methoxyphenyl)oxirane 

Downstream Products

• 777812-58-5 3-allyl-6-chloro-7,8-dimethoxy-1-(3-methoxyphenyl)-2,3,4,5-tetrahydro-1H-3-benzazepine 
• 100166-65-2 3-allyl-6-chloro-2,3,4,5-tetrahydro-1(3-hydroxyphenyl)-1H-3-benzazepine-7,8-diol 
• 100166-79-8 6-chloro-7,8-dimethoxy-1-(3-methoxyphenyl)-2,3,4,5-tetrahydro-1H-3-benzazepine 
• 67287-63-2 6-chloro-7,8-dihydroxy-1-(m-hydroxyphenyl)-2,3,4,5-tetrahydro-1H-3-benzazepine hydrobromide 

Relevant articles and documents

Dopamine receptor agonists: 3-Allyl-6-chloro-2,3,4,5-tetrahydro-1-(4-hydroxyphenyl)-1H-3-benzazepine-7 ,8-diol and a series of related 3-benzazepines

The N-allyl derivative (SK&F 85174) of 6-chloro-2,3,4,5-tetrahydro-1-(4-hydroxyphenyl)-1H-3-benzazepine-7,8-diol (SK&F 82526) not only retains the exceptional D-1 agonist potency of its parent but also displays reasonably potent D-2 agonist activity, as m

6-HALO-7,8-DIHYDROXY-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINES

7,8-Dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepines having a halo substituent at the 6-position have potent dopaminergic activity. The 6-chloro congeners are most active.

Method for 6-bromination of 1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine compounds

The preparation of 6-bromo-7,8-dimethoxy-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepines is described by direct bromination of the nucleus.