67292-34-6 Usage
Description
[1,1'-Bis(diphenylphosphino)ferrocene]dichloronickel(II), also known as dppf-dichloronickel(II), is an organometallic compound that serves as a catalyst in various chemical reactions. It is characterized by its ferrocene backbone with two diphenylphosphino groups attached to the 1,1' positions, and a dichloronickel(II) moiety. This unique structure endows it with versatile catalytic properties, making it a valuable component in the synthesis of pharmaceuticals, agrochemicals, and other organic compounds.
Uses
Used in Transition Metal-Catalyzed Reactions:
[1,1'-Bis(diphenylphosphino)ferrocene]dichloronickel(II) is used as a catalyst in transition metal-catalyzed reactions for the synthesis of pharmaceuticals and agrochemicals. Its ability to facilitate the formation of new chemical bonds and improve reaction efficiency makes it a valuable tool in the development of new drugs and agricultural products.
Used in Gem-Difluoropropargylation of Alkylzinc Reagents:
In the field of organic synthesis, [1,1'-Bis(diphenylphosphino)ferrocene]dichloronickel(II) is used as a catalyst for the gem-difluoropropargylation of alkylzinc reagents. This reaction allows for the formation of gem-difluorinated propargylic compounds, which are important building blocks in the synthesis of complex organic molecules and have potential applications in various industries.
Used in Cross-Coupling Reactions:
[1,1'-Bis(diphenylphosphino)ferrocene]dichloronickel(II) is also employed as a catalyst in cross-coupling reactions, enabling the formation of 2,3,5,6-tetrasubstituted dehydropiperidines. These compounds are valuable intermediates in the synthesis of various pharmaceuticals and agrochemicals, showcasing the versatility of this catalyst in organic synthesis.
Used in Suzuki Reaction:
In the realm of palladium-catalyzed cross-coupling reactions, [1,1'-Bis(diphenylphosphino)ferrocene]dichloronickel(II) is used as a catalyst in the Suzuki reaction. This reaction involves the coupling of an organoboron compound with an organohalide, leading to the formation of new carbon-carbon bonds. The Suzuki reaction is widely used in the synthesis of complex organic molecules, including pharmaceuticals, agrochemicals, and advanced materials.
Check Digit Verification of cas no
The CAS Registry Mumber 67292-34-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,7,2,9 and 2 respectively; the second part has 2 digits, 3 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 67292-34:
(7*6)+(6*7)+(5*2)+(4*9)+(3*2)+(2*3)+(1*4)=146
146 % 10 = 6
So 67292-34-6 is a valid CAS Registry Number.
67292-34-6Relevant articles and documents
Synthetic, electrochemical, and structural studies on heterobimetallic crown thioether complexes with Group 10 metals: The crystal structures of [Pt(9S3)(dppf)](PF6)2·CH3NO2 and [Pd(9S3)(dppf)](PF6)2·CH3NO2
Grant, Gregory J.,Carter, Shawn M.,LeBron Russell,Poullaos, Ivan M.,VanDerveer, Donald G.
, p. 683 - 690 (2001)
The syntheses, electrochemistry, and crystal structures for two new Pt(II) and Pd(II) heteroleptic bimetallic complexes with the crown trithioether 1,4,7-trithiacyclononane (9S3) and the diphosphine ligand, 1,1′-bis(diphenylphosphino)ferrocene (dppf) are reported. Both complexes have the general formula [M(9S3)(dppf)](PF6)2 (M=Pt or Pd) and exhibit the anticipated structure forming a distorted cis square planar array of two sulfur atoms from the 9S3 and two phosphorus atoms. These are, to our knowledge, the first reported examples of dppf transition metal complexes involving a thioether as the ancillary ligand. The dppf ligand functions as a bidentate chelator to a single metal center, and the third 9S3 sulfur atom does interact with the metal ion from a greater distance (Pt-S=2.8167(8) ?; Pd-S=2.7916(5) ?) to yield an elongated square pyramidal geometry. The two structures are isomorphous with very similar bond distances and angles. The values for the 31P-NMR chemical shifts (Pt=15.09 ppm, Pd=-0.47 ppm), the 195Pt-NMR chemical shift for the Pt(II) complex (-4353 ppm) and 1J(195Pt-31P) coupling constants (3511 Hz) are all consistent with a cis-MS2P2 square planar coordination sphere. The 9S3 ligand is fluxional in solution for both complexes. The electrochemistry of both complexes is dominated by a reversible Fe(II)/Fe(III) couple from the ferrocene moiety (E1/2=+721 mV for Pt(II), +732 mV for Pd(II), both versus Fc/Fc+).
Selective nickel-catalyzed fluoroalkylations of olefins
Zhang, Shaoke,Weniger, Florian,Ye, Fei,Rabeah, Jabor,Ellinger, Stefan,Zaragoza, Florencio,Taeschler, Christoph,Neumann, Helfried,Brückner, Angelika,Beller, Matthias
supporting information, p. 15157 - 15160 (2020/12/21)
Mild and selective nickel-catalyzed trifluoromethylation and perfluoroalkylation reactions of alkenes were developed to provide fluorinated olefins, including natural products, pharmaceuticals, and variety of synthetic building blocks in good to excellent
METHOD FOR PREPARATION OF FLUORO ALKYLATED COMPOUNDS BY HOMOGENEOUS NI CATALYSIS
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Page/Page column 16-17, (2020/09/08)
The invention discloses a method for the preparation of fluoro alkylated compounds by homogeneous Ni catalyzed fluoro alkylation with fluoro alkyl halides in the presence of a base.
