676496-31-4

Basic information

• Product Name: Carbamic acid, [2-[4-[[3-(aminocarbonyl)-2-pyridinyl]oxy]phenyl]ethyl]-, 1,1-dimethylethyl ester
• CAS NO: 676496-31-4
• Molecular Formula: C19H23N3O4
• Molecular Weight: 357.409
• Mol File: 676496-31-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Carbamic acid, [2-[4-[[3-(aminocarbonyl)-2-pyridinyl]oxy]phenyl]ethyl]-, 1,1-dimethylethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Carbamic acid, [2-[4-[[3-(aminocarbonyl)-2-pyridinyl]oxy]phenyl]ethyl]-, 1,1-dimethylethyl ester(676496-31-4)
• EPA Substance Registry System: Carbamic acid, [2-[4-[[3-(aminocarbonyl)-2-pyridinyl]oxy]phenyl]ethyl]-, 1,1-dimethylethyl ester(676496-31-4)

Safety Data

• Hazardous Substances Data: 676496-31-4(Hazardous Substances Data)

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 51-67-2 tyrosamine 
• 10366-35-5 2-chloronicotinamide 
• 64318-28-1 N-t-butoxycarbonyl-tyramine 

Downstream Products

• 676496-32-5 C₁₄H₁₅N₃O₂ 

Relevant articles and documents

Structure-activity relationship studies of carboxamido-biaryl ethers as opioid receptor antagonists (OpRAs). Part 1

A structurally unique and new class of opioid receptor antagonists (OpRAs) that bear no structural resemblance with morphine or endogenous opioid peptides has been discovered. A series of carboxamido-biaryl ethers were identified as potent receptor antagonists against mu, kappa and delta opioid receptors. The structure-activity relationship indicated para-substituted aryloxyaryl primary carboxamide bearing an amine tether on the distal phenyl ring was optimal for potent in vitro functional antagonism against three opioid receptor subtypes.