67688-72-6

Basic information

• Product Name: 4-(aminomethyl)benzoic acid hydrochloride
• Synonyms: 4-(aminomethyl)benzoic acid hydrochloride;4-(Aminomethyl)benzoic acid HCl;Einecs 266-903-9;Benzoic acid, 4-(aminomethyl)-, hydrochloride (1:1)
• CAS NO: 67688-72-6
• Molecular Formula: C₈H₉NO₂*ClH
• Molecular Weight: 187.6235
• EINECS: 266-903-9
• Mol File: 67688-72-6.mol
• Article Data: 2

Chemical Properties

• Melting Point: 134-136 °C
• Boiling Point: 323.1°Cat760mmHg
• Flash Point: 149.2°C
• Appearance: /
• Density: g/cm³
• Vapor Pressure: 0.00011mmHg at 25°C
• CAS DataBase Reference: 4-(aminomethyl)benzoic acid hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(aminomethyl)benzoic acid hydrochloride(67688-72-6)
• EPA Substance Registry System: 4-(aminomethyl)benzoic acid hydrochloride(67688-72-6)

Safety Data

• Hazardous Substances Data: 67688-72-6(Hazardous Substances Data)

Usage

InChI:InChI=1/C8H9NO2.ClH/c9-5-6-1-3-7(4-2-6)8(10)11;/h1-4H,5,9H2,(H,10,11);1H

Upstream product

• 53148-13-3 4-(hydroxyiminomethyl)benzoic acid methyl ester 
• 1571-08-0 methyl 4-formylbenzoate 

Downstream Products

• 470690-98-3 1-(4-carboxybenzyl)-5-hydroxymethyl-2-mercaptoimidazole 
• 953435-25-1 (S)-4-((3-(benzyloxycarbonylamino)-2,5-dioxopyrrolidin-1-yl)methyl)benzoic acid 
• 470691-06-6 1-(4-carboxybenzyl)-5-formyl-2-methylthioimidazole 
• 470691-07-7 4-(2-ethylsulfanyl-5-formyl-imidazol-1-ylmethyl)-benzoic acid 
• 470691-00-0 1-(4-carboxybenzyl)-5-hydroxymethyl-2-methylthioimidazole 
• 470691-01-1 4-(2-ethylsulfanyl-5-hydroxymethyl-imidazol-1-ylmethyl)-benzoic acid 
• 470691-08-8 4-(5-formyl-2-propylsulfanyl-imidazol-1-ylmethyl)-benzoic acid 
• 470691-02-2 4-(5-hydroxymethyl-2-propylsulfanyl-imidazol-1-ylmethyl)-benzoic acid 
• 470691-12-4 ethyl 2-azido-3-[1-(4-ethoxycarbonylbenzyl)-2-methylthioimidazol-5-yl]acrylate 
• 470691-13-5 4-[5-((Z)-2-Azido-2-ethoxycarbonyl-vinyl)-2-ethylsulfanyl-imidazol-1-ylmethyl]-benzoic acid ethyl ester 
• 470691-14-6 4-[5-((Z)-2-Azido-2-ethoxycarbonyl-vinyl)-2-propylsulfanyl-imidazol-1-ylmethyl]-benzoic acid ethyl ester 
• 33233-67-9 4-(tert-Butoxycarbonylaminomethyl)benzoic acid 

Relevant articles and documents

PREPARATION METHOD OF 4-AMINOMETHYLBENZOIC ACID

The present invention relates to a preparation method of 4-aminomethylbenzoic acid comprising the following steps: preparing 4-carboxylbenzaldehyde or an alkyl ester thereof (methyl 4-formyl benzoate); reacting the 4-carboxylbenzaldehyde or an alkyl ester thereof (methyl 4-formyl benzoate) with hydroxyamine to oximate the same; and contact reducing 4-carboxylbenzaldehyde oxime or an alkyl ester oxime thereof obtained by the oximation, through hydrogen in a sodium hydroxide aqueous solution. Since methyl 4-hydroxyiminomethylbenzoate is reacted as a raw material in the presence of an alkali, hydrogen of a relatively low pressure can be used and a purification process is also simple, thereby enabling preparation of 4-aminomethylbenzoic acid with a low cost and high yield.