67759-79-9

Basic information

• Product Name: 2-(2-methylamino)phenyl-2-propanol
• CAS NO: 67759-79-9
• Molecular Weight: 165.235
• Mol File: 67759-79-9.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 2-(2-methylamino)phenyl-2-propanol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2-methylamino)phenyl-2-propanol(67759-79-9)
• EPA Substance Registry System: 2-(2-methylamino)phenyl-2-propanol(67759-79-9)

Safety Data

• Hazardous Substances Data: 67759-79-9(Hazardous Substances Data)

Upstream product

• 15833-00-8 o-aminophenyldimethylcarbinol 
• 107125-70-2 lithium N-phenyl-N-methylcarbamate 
• 67-64-1 acetone 
• 917-54-4 methyllithium 
• 85-91-6 Methyl N-methylanthranilate 
• 75-16-1 methylmagnesium bromide 
• 118-92-3 anthranilic acid 
• 134-20-3 2-carbomethoxyaniline 
• 100-61-8 N-methylaniline 
• 10328-92-4 N-Methylisatoic anhydride 
• 57772-48-2 1,2-dihydro-4,4-dimethyl-4H-3,1-benzoxazine 

Downstream Products

• 86724-46-1 N-(2-Isopropenyl-phenyl)-N-methyl-N'-trimethylsilanylmethyl-formamidine 
• 54833-65-7 (+/-)-1-benzoyl-3a,8-dimethyl-(3ar,8ac)-1,2,3,3a,8,8a-hexahydro-pyrrolo[2,3-b]indole 
• 202276-29-7 N-methyl-N-[2-(1-methyl-1-trimethylsilanyloxyethyl)phenyl]-3-phenylpropionamide 
• 202276-25-3 N-methyl-N-[2-(1-methyl-1-trimethylsilanyloxyethyl)phenyl]acrylamide 
• 202276-13-9 methyl-[2-(1-methyl-1-trimethylsilanyloxyethyl)phenyl]amine 
• 7117-17-1 N-methyl-2-(1-methylethenyl)benzenamine 

Relevant articles and documents

Chemoselectivity for Alkene Cleavage by Palladium-Catalyzed Intramolecular Diazo Group Transfer from Azide to Alkene

Alkenes can be cleaved by means of the (3+2) cycloaddition and subsequent cycloreversion of 1,3-dipoles, classically ozone (O3), but the azide (R?N3) variant is rare. Chemoselectivity for these azide to alkene diazo group transfers (DGT) is typically disfavored, thus limiting their synthetic utility. Herein, this work discloses a palladium-catalyzed intramolecular azide to alkene DGT, which grants chemoselectivity over competing aziridination. The data support a catalytic cycloreversion mechanism distinct from other known metal-catalyzed azide/alkene reactions: nitrenoid/metalloradical and (3+2) cycloadditions. Kinetics experiments reveal an unusual mechanistic profile in which the catalyst is not operative during the rate-controlling step, rather, it is active during the product-determining step. Catalytic DGT was used to synthesize N-heterocyclic quinazolinones, a medicinally relevant structural core. We also report on the competing aziridination and subsequent ring expansion to another N-heterocyclic core structure of interest, benzodiazepinones.

Studies on the Benzoxazine Series. 2- Preparation and 1H and 13C NMR Structural Study of Some Substituted 1,2-Dihydro-4H-3,1-benzoxazines

In addition to the parent compounds, nine methyl-substituted 1,2-dihydro-4H-3,1-benzoxazines with and without N-methyl substitution were prepared.The chain tautomer could only be detected in the case of 1,2-dihydro-2-(p-nitrophenyl)-4H-3,1-benzoxazine in

Alkaloid synthesis via the intramolecular imidate methylide 1,3-dipolar cycloaddition reaction

A concise synthesis for the neurotoxic physostigmine alkaloid d,l-eserethole is described which relys upon an intramolecular cycloaddition reaction involving a "non-stabilized" imidate methylide and an unactivated alkene. The facility of this cyclization