68020-40-6

Basic information

• Product Name: 7-amino-2,3-dihydro-8-<(4-chlorophenyl)methyl>-6-nitrosoimidazo<1,2-a>pyrimidin-5(8H)-one
• Synonyms: 7-amino-2,3-dihydro-8-<(4-chlorophenyl)methyl>-6-nitrosoimidazo<1,2-a>pyrimidin-5(8H)-one
• CAS NO: 68020-40-6
• Molecular Weight: 305.724
• Mol File: 68020-40-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 7-amino-2,3-dihydro-8-<(4-chlorophenyl)methyl>-6-nitrosoimidazo<1,2-a>pyrimidin-5(8H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 7-amino-2,3-dihydro-8-<(4-chlorophenyl)methyl>-6-nitrosoimidazo<1,2-a>pyrimidin-5(8H)-one(68020-40-6)
• EPA Substance Registry System: 7-amino-2,3-dihydro-8-<(4-chlorophenyl)methyl>-6-nitrosoimidazo<1,2-a>pyrimidin-5(8H)-one(68020-40-6)

Safety Data

• Hazardous Substances Data: 68020-40-6(Hazardous Substances Data)

Upstream product

• 68020-39-3 2-<<(4-chlorophenyl)methyl>amino>-2-imidazoline 
• 3849-21-6 ethyl cyanoglyoxylate-2-oxime 
• 104-86-9 4-chlorobenzylamine 

Downstream Products

• 68020-55-3 2-bromo-4-<(4-chlorophenyl)methyl>-6,7-dihydro-3H-imidazo<1,2-a>purin-9(4H)-one hydrobromide 
• 75185-03-4 4-<(4-chlorophenyl)methyl>-6,7-dihydro-2-(methylthio)-3H-imidazo<1,2-a>purin-9(5H)-one 
• 75185-05-6 2-Bromo-4-(4-chloro-benzyl)-1-methyl-1,4,6,7-tetrahydro-imidazo[1,2-a]purin-9-one 
• 75185-04-5 2-amino-4-[(4-chlorophenyl)methyl]-6,7-dihydro-1-methyl-1H-imidazo[1,2-a]purin-9(4H)-one 
• 75184-93-9 4-(4-Chloro-benzyl)-1,2-dimethyl-1,4,6,7-tetrahydro-imidazo[1,2-a]purin-9-one 
• 75217-20-8 4-(4-Chloro-benzyl)-9-methylsulfanyl-6,7-dihydro-4H-imidazo[1,2-a]purine 
• 75185-16-9 1-(2-aminoethyl)-3-<(4-chlorophenyl)methyl>-7(9H)-purine-2,6(1H,3H)-dione 
• 75185-02-3 4-<(4-chlorophenyl)methyl>-2,3,6,7-tetrahydro-2-thioxo-1H-imidazo<1,2-a>purin-9(4H)-one 
• 75184-92-8 4-(4-Chloro-benzyl)-1-methyl-1,4,6,7-tetrahydro-imidazo[1,2-a]purin-9-one 
• 75185-06-7 4-<(4-chlorophenyl)methyl>-6,7-dihydro-3H-imidazo<1,2-a>purine-9(4H)-thione 
• 75199-29-0 4-(4-Chloro-benzyl)-3,4,6,7-tetrahydro-imidazo[1,2-a]purin-9-ylideneamine 
• 75185-01-2 4-<(4-chlorophenyl)methyl>-3H-imidazo<1,2-a>purin-9(4H)-one 
• 75185-17-0 4-[(4-chlorophenyl)methyl]-7,8-dihydro-3H-imidazo[2,1-i]purin-5(4H)-one 
• 79013-35-7 1-butyl-4-(4-chloro-benzyl)-1,4,6,7-tetrahydro-imidazo[1,2-a]purin-9-one 

Relevant articles and documents

Substituted 6,7-dihydroimidazo[1,2-al]purin-9 (4H)-ones

The synthesis of a series of substituted 6,7-dihydroimidazo[1,2-a]purin-9(4H)-ones is described. Several members of the series exhibit enhanced antiallergic and bronchodilator activity and reduced side effects as compared to theophylline. Structure-activity relationships and metabolic considerations are discussed for the series. Analogues substituted with a 4-(4-chlorobenzyl) moiety, such as 33 and 40, show an optimal balance of antiallergic and bronchodilator activity and are of particular interest. Compound 33 is significantly more potent than theophylline against both metacholine- and antigen-induced bronchospasms, does not affect spontaneous motor activity, and shows minimal cardiovascular effects in the rat.