680622-83-7 Usage
Molecular weight
757.92 g/mol
Structural features
Fluoren-9-ylmethyl ester group
2,5,8,11-tetraoxa-14,17-diazaoctadecan-18-oic acid backbone
Amino groups (e.g., 2-amino-1H-purin-6-yl and 4,4-dimethyl-2,6-dioxocyclohexylideneethylamino)
Oxo (carbonyl) group at position 15
1H-purin-6-yloxymethyl group attached to a phenyl ring
Stereochemistry
(16S) configuration at position 16
Classification
Derivative of oxa acid
Potential applications
Medicinal, pharmaceutical, or biochemical research, given its intricate structure and biologically relevant functional groups.
Check Digit Verification of cas no
The CAS Registry Mumber 680622-83-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,8,0,6,2 and 2 respectively; the second part has 2 digits, 8 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 680622-83:
(8*6)+(7*8)+(6*0)+(5*6)+(4*2)+(3*2)+(2*8)+(1*3)=167
167 % 10 = 7
So 680622-83-7 is a valid CAS Registry Number.
680622-83-7Relevant articles and documents
Synthesis and characterization of bifunctional probes for the specific labeling of fusion proteins
Kindermann, Maik,Sielaff, India,Johnsson, Kai
, p. 2725 - 2728 (2004)
Labeling proteins with synthetic probes is important for studying and characterizing protein function. We have recently introduced a general method for the specific in vivo and in vitro labeling of fusion proteins that is based on the reaction of O6-alkylguanine-DNA alkyltransferase (AGT) with O6-benzylguanine derivatives. Here we report two complementary routes for the synthesis of O6-benzylguanine derivatives, which allow for the labeling of AGT fusion proteins with bifunctional synthetic probes and demonstrate the specific labeling of AGT fusion proteins with these probes. These molecules should become useful tools for various applications in functional proteomics.
