68104-99-4 Usage
General Description
4-CYCLOPENTYL-3-OXO-BUTYRIC ACID ETHYL ESTER, also known as ethyl 4-cyclopentyl-3-oxobutanoate, is a chemical compound with the molecular formula C10H16O3. It is an ethyl ester derivative of 4-cyclopentyl-3-oxo-butyric acid, which is a precursor in the synthesis of certain pharmaceuticals, especially those related to the treatment of neurological disorders. 4-CYCLOPENTYL-3-OXO-BUTYRIC ACID ETHYL ESTER is commonly used as an intermediate in organic synthesis and is known for its potential applications in medicinal chemistry. It is a clear, colorless liquid with a fruity odor, and it is important to handle this chemical with caution as it may be harmful if ingested or inhaled.
Check Digit Verification of cas no
The CAS Registry Mumber 68104-99-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,8,1,0 and 4 respectively; the second part has 2 digits, 9 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 68104-99:
(7*6)+(6*8)+(5*1)+(4*0)+(3*4)+(2*9)+(1*9)=134
134 % 10 = 4
So 68104-99-4 is a valid CAS Registry Number.
InChI:InChI=1/C11H18O3/c1-2-14-11(13)8-10(12)7-9-5-3-4-6-9/h9H,2-8H2,1H3
68104-99-4Relevant articles and documents
Affinity of 3-acyl substituted 4-quinolones at the benzodiazepine site of GABAA receptors
Lager, Erik,Nilsson, Jakob,stergaard Nielsen, Elsebet,Nielsen, Mogens,Liljefors, Tommy,Sterner, Olov
, p. 6936 - 6948 (2008/12/21)
The finding that alkyl 1,4-dihydro-4-oxoquinoline-3-carboxylate and N-alkyl-1,4-dihydro-4-oxoquinoline-3-carboxamide derivatives may be high-affinity ligands at the benzodiazepine binding site of the GABAA receptor, prompted a study of 3-acyl-1,4-dihydro-4-oxoquinoline (3-acyl-4-quinolones). In general, the affinity of the 3-acyl derivatives was found to be comparable with the 3-carboxylate and the 3-carboxamide derivatives, and certain substituents (e.g., benzyl) in position 6 were again shown to be important. As it is believed that the benzodiazepine binding site is situated between an α- and a γ-subunit in the GABAA receptor, selected compounds were tested on the α1β2γ2s, α2β2γ2s and α3β2γ2s GABAA receptor subtypes. The 3-acyl-4-quinolones display various degrees of selectivity for α1- versus α2- and α3-containing receptors, and high-affinity ligands essentially selective for α1 over α3 were developed.
