681287-04-7Relevant articles and documents
An Unusual Reverse Turn Structure Adopted by a Furanoid Sugar Amino Acid Incorporated in Gramicidin S
Grotenbreg, Gijsbert M.,Timmer, Mattie S. M.,Llamas-Saiz, Antonio L.,Verdoes, Martijn,Van Der Marel, Gijsbert A.,Van Raaij, Mark J.,Overkleeft, Herman S.,Overhand, Mark
, p. 3444 - 3446 (2004)
A new reverse turn, replacing one of the native type II′ β-turns in the cyclic peptide antibiotic gramicidin S, induced by a furanoid sugar amino acid is revealed. The C3-hydroxyl function plays a pivotal role by acting as a H-bond acceptor, co