68279-09-4

Basic information

• Product Name: N-(4-bromophenyl)-α-(4-phenyl)-nitrone
• CAS NO: 68279-09-4
• Molecular Weight: 276.132
• Mol File: 68279-09-4.mol
• Article Data: 13

Chemical Properties

• CAS DataBase Reference: N-(4-bromophenyl)-α-(4-phenyl)-nitrone(CAS DataBase Reference)
• NIST Chemistry Reference: N-(4-bromophenyl)-α-(4-phenyl)-nitrone(68279-09-4)
• EPA Substance Registry System: N-(4-bromophenyl)-α-(4-phenyl)-nitrone(68279-09-4)

Safety Data

• Hazardous Substances Data: 68279-09-4(Hazardous Substances Data)

Upstream product

• 586-78-7 para-nitrophenyl bromide 
• 1137-96-8 N-(benzylidene)aniline N-oxide 
• 100-52-7 benzaldehyde 
• 10468-46-9 N-(4-bromophenyl)hydroxylamine 
• 3623-23-2 4-bromonitrosobenzene 

Downstream Products

• 37871-90-2 (3S,4R)-1-(4-bromophenyl)-3,4-diphenyl-2-azetidinone 

Relevant articles and documents

Rhodium-catalyzed cyclization of diynes with nitrones: A formal [2+2+5] approach to bridged eight-membered heterocycles

N-aryl-substituted nitrones were employed as fiveatom coupling partners in the rhodium-catalyzed cyclization with diynes. In this reaction, the nitrone moiety served as a directing group for the catalytic C-H activation of the N-aryl ring. This formal [2+2+5] approach allows rapid access to bridged eight-membered heterocycles with broad substrate scope. The results of this study may provide new insight into the chemistry of nitrones and find applications in the synthesis of other heterocycles,.

Tandem Chiral Cu(II) Phosphate-Catalyzed Deoxygenation of Nitrones/Enantioselective Povarov Reaction with Enecarbamates

A new catalytic enantioselective tandem deoxygenation/aza-Diels-Alder reaction of nitrones with enecarbamates was serendipitously discovered in the presence of chiral copper(II) diphosphate complexes. This process affords a wide range of 4-aminotetrahydroquinolines in respectable yields under mild conditions with good to excellent ee values.

Preparation method of 2-amino-5-halogen phenol compounds

The invention relates to a preparation method of 2-amino-5-halogen phenol compounds. The compounds are very important intermediates in fine chemistry. Due to the ortho-position special relation of a hydroxyl group in an amino group, the compounds are important raw materials for preparing heterocyclic compounds such as the benzoxazolone compound and the benzothiazolone compound which are intermediates with the important value in medical drugs. The 2-amino-5-halogen phenol compounds can serve as anti-cancer drugs such as hydroxamic acid anti-cancer drugs and intermediates of dye and have wide application in chemical engineering, soft matter, materials and the like. According to the method, nitrone is taken as a raw material and easily prepared from a halogen nitrobenzene compound; raw materials of the halogen nitrobenzene compound are low in cost and wide in source.