683-57-8

Basic information

• Product Name: 2-BROMOACETAMIDE
• Synonyms: 2-bromo-acetamid;Acetamide, 2-bromo-;BROMOACETAMIDE;2-BROMOACETAMIDE;2-Bromoacetamide98%;2-Bromoacetamide,97%;2-BROMOACETAMIDE pure;2-BroMoacetaMide, 98% 25GR
• CAS NO: 683-57-8
• Molecular Formula: C₂H₄BrNO
• Molecular Weight: 137.96
• EINECS: 226-270-1
• Product Categories: Amides;Carbonyl Compounds;Organic Building Blocks
• Mol File: 683-57-8.mol
• Article Data: 2

Chemical Properties

• Melting Point: 87-91 °C(lit.)
• Boiling Point: 271.6oC at 760 mmHg
• Flash Point: 118.1oC
• Appearance: White/Crystalline Powder
• Density: 1.4243 (rough estimate)
• Vapor Pressure: 0.00638mmHg at 25°C
• Refractive Index: 1.4740 (estimate)
• Storage Temp.: Store at RT.
• Solubility: 160g/l
• PKA: 14.79±0.40(Predicted)
• BRN: 1739073
• CAS DataBase Reference: 2-BROMOACETAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-BROMOACETAMIDE(683-57-8)
• EPA Substance Registry System: 2-BROMOACETAMIDE(683-57-8)

Safety Data

• Hazard Codes: T,C
• Statements: 25-34-20/21/22
• Safety Statements: 26-27-36/37/39-45
• RIDADR: UN 2923 8/PG 2
• WGK Germany: 3
• RTECS: AB4587000
• F: 10
• HazardClass: 8
• PackingGroup: III
• Hazardous Substances Data: 683-57-8(Hazardous Substances Data)

Usage

Description

2-Bromoacetamide is an organic compound with the chemical formula C2H4BrNO. It is a white crystalline solid that is soluble in water and has a slight odor. 2-BROMOACETAMIDE is known for its reactivity and is commonly used as a synthetic intermediate in the preparation of various organic compounds.

Uses

Used in Pharmaceutical Industry:
2-Bromoacetamide is used as a synthetic intermediate for the preparation of (2-carbamoylmethoxy-5-chloro-benzyl)-carbamic acid tert-butyl ester, which is a key compound in the development of pharmaceuticals. It plays a crucial role in the synthesis of drugs with potential therapeutic applications.
Used in Biochemistry Research:
2-Bromoacetamide is also used as a precursor to dehydropeptidase I inactivator, an enzyme that is involved in the regulation of various biological processes. By inactivating this enzyme, researchers can study its function and its role in different diseases, which can lead to the development of new therapeutic strategies.

Hazard

A poison by ingestion. Moderately toxic by skin contact. A severe skin and eye irritant.

InChI:InChI=1/C2H4BrNO/c3-1-2(4)5/h1H2,(H2,4,5)

Upstream product

• 35070-76-9 N-chlorobromoacetamide 
• 110-83-8 cyclohexene 
• 7664-41-7 ammonia 

Downstream Products

• 871878-51-2 nitrilotri-acetic acid diamid-anilide 
• 50785-26-7 salicyloyloxy-acetic acid amide 
• 590-17-0 cyanomethyl bromide 
• 13330-87-5 2(Acetamido)thioessigsaeure 
• 42239-75-8 4-phenylpiperazine-2,6-dione 
• 99168-31-7 phenylimino-di-acetic acid diamide 
• 111298-19-2 8-carbamoylmethyl-8-methyl-3-tropoyloxy-nortropanium; bromide 
• 13610-65-6 2-(2-oxo-benzooxazol-3-yl)-acetamide 
• 35382-70-8 2-(2-oxo-4H-benzo[d][1,3]oxazin-1-yl)-acetamide 
• 57837-02-2 2-(2,6-Diethyl-phenylamino)-acetamide 
• 52121-18-3 2-(2-ethylcarbamoylimino-5-nitro-thiazol-3-yl)-acetamide 
• 52121-02-5 N-ethylcarbamoyl-N-(5-nitro-thiazol-2-yl)-glycine amide 
• 35382-75-3 2-(6-chloro-2-oxo-4-phenyl-4H-benzo[d][1,3]oxazin-1-yl)-acetamide 
• 94360-69-7 2-[3-Cyano-4-(4-methoxy-phenyl)-6-phenyl-pyridin-2-ylsulfanyl]-acetamide 

Relevant articles and documents

Inhibitors of sorotonin N-acetyltransferase

This invention is directed to a compound having the formula I. STR1 This invention is directed to a pharmaceutical composition comprising a compound which inhibits serotonin N-acetyltransferase having the formula I and a pharmaceutical acceptable carrier. The present invention relates to novel compounds and analogs which inhibit the serotonin N-acetyltransferase enzyme, and to processes for their preparation.