68314-38-5 Usage
Description
(6R,7R)-3-Chloromethyl-7-methoxy-8-oxo-7-(p-toluoylamino)-5-oxa-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid diphenylmethyl ester is a complex organic molecule characterized by its bicyclic ring structure and the presence of multiple functional groups. (6R,7R)-3-Chloromethyl-7-methoxy-8-oxo-7-(p-toluoylamino)-5-oxa-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid diphenylmethyl ester features a chlorine atom, a methoxy group, a ketone group, and an ester group, along with a toluoylamino substituent. Its structural complexity suggests potential as a drug candidate or a key intermediate in the synthesis of pharmaceutical compounds, warranting further investigation into its biological activities and medicinal properties within the field of medicinal chemistry.
Uses
Used in Pharmaceutical Industry:
(6R,7R)-3-Chloromethyl-7-methoxy-8-oxo-7-(p-toluoylamino)-5-oxa-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid diphenylmethyl ester is used as a potential drug candidate for its unique structural features and functional groups that may contribute to biological activities and medicinal properties. Its complex nature positions it as a promising compound for the development of new therapeutic agents.
Used in Medicinal Chemistry Research:
In the field of medicinal chemistry, (6R,7R)-3-Chloromethyl-7-methoxy-8-oxo-7-(p-toluoylamino)-5-oxa-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid diphenylmethyl ester serves as a key intermediate in the synthesis of pharmaceutical compounds. Its structural complexity and the presence of various functional groups make it an interesting subject for further study and exploration, potentially leading to the discovery of novel drugs and therapeutic agents.
Check Digit Verification of cas no
The CAS Registry Mumber 68314-38-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,8,3,1 and 4 respectively; the second part has 2 digits, 3 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 68314-38:
(7*6)+(6*8)+(5*3)+(4*1)+(3*4)+(2*3)+(1*8)=135
135 % 10 = 5
So 68314-38-5 is a valid CAS Registry Number.
68314-38-5Relevant articles and documents
A method for the preparation of fluorine oxygen spore sodium
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Paragraph 0024-0026; 0027-0029, (2017/12/02)
The invention belongs to a new flomoxef sodium preparation method, and particularly relates to a preparation method of flomoxef sodium. The method comprises the steps of: enabling a compound (I) to react with methyl alcohol to generate a compound (II) under the catalysis of ceric ammonium nitrate, next connecting with a tetrazole side chain to obtain a compound (III), removing an amino protection group and a hydroxyl protection group under enzymolysis to obtain a compound (IV), reacting with an intermediate of difluromethylation mercaptoacetic acid active ester to obtain a compound (V), removing the hydroxyl protection group under the effect of trifluoroacetic acid to obtain a compound (VI), and finally obtaining the flomoxef sodium (VII) through a formed sodium salt reaction. The reaction route is as follows. The method provided by the invention has the following advantages that the reaction operation is simple, convenient and reliable, the reaction route is short, the aims of going green and environmental protection, and high productivity are realized, the after-treatment is easy and high-purity flomoxef sodium is obtained.
Design, synthesis and antibacterial activity of novel 1-oxacephem analogs
He, Yi,Wu, Jian Bo,Lei, Fan,Chen, Pei,Hai, Li,Wu, Yong
, p. 407 - 410 (2012/05/20)
A series of 1-oxacephem analogs were synthesized and their antibacterial properties against five strains of Gram-positive and Gram-negative bacteria were evaluated in vitro while ceftazidine was selected as control. Some of the tested compounds, compound 12c in particular, showed more active against three selected strains than the standard.