6833-15-4

Basic information

• Product Name: 4-CHLOROBENZANILIDE
• Synonyms: 4-CHLOROBENZANILIDE;4-Chloro-N-phenylbenzamide;N-Phenyl-4-chlorobenzamide;N-Phenyl-p-chlorobenzamide;4-Chlorobenzanilide,98%
• CAS NO: 6833-15-4
• Molecular Formula: C₁₃H₁₀ClNO
• Molecular Weight: 231.68
• Product Categories: Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts
• Mol File: 6833-15-4.mol
• Article Data: 146

Chemical Properties

• Melting Point: 199-201 °C(lit.)
• Boiling Point: 288.6 °C at 760 mmHg
• Flash Point: 128.3 °C
• Appearance: /Solid
• Density: 1.285 g/cm³
• Vapor Pressure: 0.00232mmHg at 25°C
• Refractive Index: 1.649
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 4-CHLOROBENZANILIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-CHLOROBENZANILIDE(6833-15-4)
• EPA Substance Registry System: 4-CHLOROBENZANILIDE(6833-15-4)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-37/39
• WGK Germany: 3
• Hazardous Substances Data: 6833-15-4(Hazardous Substances Data)

Usage

InChI:InChI=1/C13H10ClNO/c14-11-8-6-10(7-9-11)13(16)15-12-4-2-1-3-5-12/h1-9H,(H,15,16)

Upstream product

• 2998-98-3 (Z)-(4-chlorophenyl)(phenyl)methanone oxime 
• 104-88-1 4-chlorobenzaldehyde 
• 103-71-9 phenyl isocyanate 
• 108-90-7 chlorobenzene 
• 122-01-0 4-chloro-benzoyl chloride 
• 62-53-3 aniline 
• 1871-38-1 phenyl 4-chlorobenzoate 
• 28122-82-9 S-phenyl 4-chlorobenzothioate 
• 74-11-3 para-chlorobenzoic acid 
• 59318-25-1 p-Chlorobenzoylthiochlorosulfit 
• 13014-48-7 4-chlorobenzoyl cyanide 
• 109310-00-1 N,O-bis-(4-chloro-benzoyl)-N-phenyl-hydroxylamine 
• 67-56-1 methanol 
• 14064-15-4 (4-chlorophenyl)trimethylstannane 

Downstream Products

• 65786-54-1 4'-chloro-4-dimethylamino-2-methyl-benzophenone 
• 105702-86-1 4-chloro-4'-(N-methyl-anilino)-benzophenone 
• 37613-10-8 4-chloro-N-phenyl-benzimidoyl chloride 
• 129120-25-8 (4-chlorophenyl)(4-(dimethylamino)phenyl)methanone 
• 91790-87-3 N,N'-diphenyl-4-chlorobenzamidine 
• 104689-75-0 (4-chlorophenyl)(4-(diethylamino)phenyl)methanone 
• 54595-71-0 6-chloro-1'-methyl-spiro[isobenzofuran-1,4'-piperidin]-3-one 
• 54595-72-1 1'-benzyl-6-chloro-spiro[isobenzofuran-1,4'-piperidin]-3-one 
• 5892-88-6 (4-Chloro-benzoyl)-phenyl-carbamic acid 2-chloro-1-methyl-ethyl ester 
• 5892-83-1 (4-Chloro-benzoyl)-phenyl-carbamic acid 2-methoxy-1-methyl-ethyl ester 
• 5892-74-0 (4-Chloro-benzoyl)-phenyl-carbamic acid isopropyl ester 
• 122399-73-9 3-<4-(4-chlorobenzoylamino)benzoyl>acrylic acid 
• 63471-86-3 4-[4-(4-chloro-benzoylamino)-phenyl]-4-oxo-butyric acid 
• 146516-72-5 4-chloro-2-trimethylsilyl-benzanilide 

Relevant articles and documents

TBAI-catalyzed C–N bond formation through oxidative coupling of benzyl bromides with amines: a new avenue to the synthesis of amides

A new green approach for the synthesis of amide through TBAI-catalyzed oxidative coupling of benzyl bromides with amine was developed in the presence of tert-butyl hydroperoxide (TBHP) as an oxidant. Various electron-donating and withdrawing groups containing benzyl bromides and various amines, were subjected to the reaction and transformed to the corresponding amide in good to excellent yields.

Cobalt-Catalyzed Deoxygenative Hydroboration of Nitro Compounds and Applications to One-Pot Synthesis of Aldimines and Amides

The commercially available and bench-stable Co(acac)2 ligated with bis[(2-diphenylphosphino)phenyl] ether (dpephos) was employed for selective room temperature hydroboration of nitro compounds with HBPin (TOF up to 4615 h?1), tolerating halide, hydroxy, amino, ether, ester, lactone, amide and heteroaromatic functionalities. These reactions offered a direct access to a variety of N-borylamines RN(H)BPin, which were in situ treated with aldehydes and carboxylic acids to produce a series of aldimines and secondary carboxamides without the need for dehydrating and/or coupling reagents. Combination of these transformations in a sequential one-pot manner allowed for direct and selective synthesis of aldimines and secondary carboxamides from readily available and inexpensive nitro compounds.

Activated charcoal supported copper nanoparticles: A readily available and inexpensive heterogeneous catalyst for the N-arylation of primary amides and lactams with aryl iodides

A novel heterogeneous copper catalyst has been developed by supporting copper nanoparticles on activated charcoal via in situ reducing copper(II) with aqueous hydrazine as reductant. The characterization of Cu/C catalyst showed that the Cu0 nano-particles were formed on the surface of charcoal. This catalyst displayed good catalytic activities toward the N-arylation of primary amides and lactams with aryl iodides.