68353-23-1

Basic information

• Product Name: 14-ForMyldihydrorutaecarpine
• Synonyms: 14-ForMyldihydrorutaecarpine
• CAS NO: 68353-23-1
• Molecular Formula: C19H15N3O2
• Molecular Weight: 317.3413
• Mol File: 68353-23-1.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 638.5±55.0 °C(Predicted)
• Appearance: /
• Density: 1.47±0.1 g/cm3(Predicted)
• PKA: 16.56±0.20(Predicted)
• CAS DataBase Reference: 14-ForMyldihydrorutaecarpine(CAS DataBase Reference)
• NIST Chemistry Reference: 14-ForMyldihydrorutaecarpine(68353-23-1)
• EPA Substance Registry System: 14-ForMyldihydrorutaecarpine(68353-23-1)

Safety Data

• Hazardous Substances Data: 68353-23-1(Hazardous Substances Data)

Usage

Description

14-Formyldihydrorutaecarpine is a novel alkaloid compound that has been identified for its potential antioxidant properties. It is derived from natural sources and has demonstrated the ability to inhibit the formation of oxygen radicals, particularly through the action of human neutrophils. This unique characteristic positions 14-formyldihydrorutaecarpine as a promising candidate for various applications in different industries, particularly in the realm of health and medicine.

Uses

Used in Pharmaceutical Industry:
14-Formyldihydrorutaecarpine is used as a potential antioxidant agent for its ability to inhibit oxygen radical formation. This property makes it a valuable component in the development of treatments and therapies aimed at combating oxidative stress-related conditions and diseases.
Used in Nutraceutical Industry:
In the nutraceutical sector, 14-formyldihydrorutaecarpine is used as a dietary supplement or functional ingredient to support overall health and well-being. Its antioxidant effects can contribute to the maintenance of a balanced immune system and the prevention of cell damage caused by free radicals.
Used in Cosmetic Industry:
14-Formyldihydrorutaecarpine can be utilized in cosmetic products as an antioxidant agent to protect the skin from environmental stressors and promote skin health. Its ability to neutralize oxygen radicals may help in reducing signs of aging, inflammation, and other skin-related issues.
Used in Agricultural Industry:
In agriculture, 14-formyldihydrorutaecarpine may be employed as a natural antioxidant to improve the shelf life and quality of produce. Its application can help in reducing post-harvest losses and maintaining the nutritional value of agricultural products.

Upstream product

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• 2258-42-6 formyl acetic anhydride 
• 60941-86-8 3-<2-(3-indolyl)ethyl>-4(3H)-quinazolinone 
• 61-54-1 tryptamine 
• 118-48-9 isatoic anhydride 
• 33284-02-5 2-amino-N-[2-(1H-indol-3-yl)ethyl]benzamide 
• 95274-45-6 3-<2-(N-formyl-3-indolyl)ethyl>-4-(3H)-quinazolinone 
• 95274-46-7 3-<2-(N-acetyl-3-indolyl)ethyl>-4(3H)-quinazolinone 

Relevant articles and documents

Studies of Rutaecarpine and Related Quinazolinocarboline Alkaloids

Quinazolinocarboline alkaloids, e.g., rutaecarpine (1), can readily be synthesized by treating tryptamine with 2-(trifluoromethyl)-4H-3,1-benzoxazin-4-one (quickly generated in situ from trifluoroacetic anhydride (TFAA) and 2H-3,1-benzoxazine-2,4(1H)-dione.The product formed, 3--2-(trifluoromethyl)-4-(3H)-quinazolinone (5), is then cyclized (HCl/HOAc) to 13b-(trifluoromethyl)-13b,14-dihydrorutaecarpine (6), whereupon CF3H is eliminated by treatment with base.The sequence can conveniently be performed as a three-reaction one-pot procedure giving rutaecarpine (1) in 99percent yield within 3h.The approach can readily be extended to the synthesis of evodiamine (2), 13,13b-dehydroevodiamine (38a), and 13b,14-dihydrorutaecarpine (21).Thus treatment of 3--4(3H)-quinazolinone (19) with TFAA affected cyclization to 13b-(trifluoroacetyl)-13b,14-dihydrorutaecarpine (20), which can be readily hydrolyzed to 13b,14-dihydrorutaecarpine (21).