68674-65-7Relevant articles and documents
Graphene oxide (GO) or reduced graphene oxide (rGO): Efficient catalysts for one-pot metal-free synthesis of quinoxalines from 2-nitroaniline
Roy, Babli,Ghosh, Sujit,Ghosh, Pranab,Basu, Basudeb
supporting information, p. 6762 - 6767 (2016/01/30)
A straightforward one-pot preparation of library of quinoxalines from 2-nitroanilines under entirely metal-free conditions is described. Initial reduction of nitroaniline with hydrazine hydrate is efficiently catalyzed by graphene oxide (GO) or reduced graphene oxide (rGO), and further one-pot tandem reactions with 1,2-dicarbonyl compounds or with α-hydroxy ketones afford quinoxalines in excellent yields. The catalyst is recovered, characterized, and found to be recyclable for consecutive four runs examined with appreciable conversions.
A green synthesis of quinoxalines and 2,3-dihydropyrazines
Delpivo, Camilla,Micheletti, Gabriele,Boga, Carla
, p. 1546 - 1552 (2013/06/27)
Quinoxaline and dihydropyrazine derivatives were obtained in high yields by simple addition of 1,2-diamines and 1,2-dicarbonyl compounds in water. In some cases, the products spontaneously precipitated from the reaction mixture, making it possible to recover and reuse the mother liquor for further condensations. The very mild reaction conditions, the high yields of the products, and the absence of any catalyst make this methodology an efficient and green route to quinoxalines and dihydropyrazines. Georg Thieme Verlag Stuttgart New York.
La(OTf)3 catalyzed synthesis of quinoxalines
Raju, B. China,Ramachandra
experimental part, p. 756 - 759 (2012/06/30)
Lanthanum trifluoromethanesulfonate is found to be an efficient and highly effective catalyst for the synthesis of quinoxalines 3a-l by the condensation of aromatic 1,2-diamines 1 with 1,2-diketones 2 under ambient conditions. The method is simple and eff
